Technical Performance of Two-Dimensional Shear Wave Elastography for Measuring Liver Stiffness: A Systematic Review and Meta-Analysis

被引：32

作者：

Kim, Dong Wook ^{[1
,2
]}

Suh, Chong Hyun ^{[1
,2
]}

Kim, Kyung Won ^{[1
,2
]}

Pyo, Junhee ^{[3
]}

Park, Chan ^{[4
]}

Jung, Seung Chai ^{[1
,2
]}

机构：

[1] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Radiol, 88 Olymp Ro 43 Gil, Seoul 05505, South Korea

[2] Univ Ulsan, Coll Med, Asan Med Ctr, Res Inst Radiol, 88 Olymp Ro 43 Gil, Seoul 05505, South Korea

[3] Univ Utrecht, Dept Pharmaceut Sci, WHO Collaborating Ctr Pharmaceut Policy & Regulat, Utrecht, Netherlands

[4] Chonnam Natl Univ Hosp, Dept Radiol, Gwangju, South Korea

来源：

KOREAN JOURNAL OF RADIOLOGY | 2019年 / 20卷 / 06期

基金：

新加坡国家研究基金会;

关键词：

Elasticity imaging techniques; Liver; Meta-analysis; Ultrasonography; RADIATION FORCE IMPULSE; PREDICTING DIFFERENT STAGES; DIAGNOSTIC-TEST ACCURACY; CHRONIC HEPATITIS-B; TRANSIENT ELASTOGRAPHY; ULTRASOUND ELASTOGRAPHY; QUANTITATIVE ELASTOGRAPHY; SPLEEN STIFFNESS; CLINICAL-USE; FIBROSIS;

D O I：

10.3348/kjr.2018.0812

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Objective: To assess the technical performance of two-dimensional shear wave elastography (2D-SWE) for measuring liver stiffness. Materials and Methods: The Ovid-MEDLINE and EMBASE databases were searched for studies reporting the technical performance of 2D-SWE, including concerns with technical failures, unreliable measurements, interobserver reliability, and/or intraobserver reliability, published until June 30, 2018. The pooled proportion of technical failure and unreliable measurements was calculated using meta-analytic pooling via the random-effects model and inverse variance method for calculating weights. Subgroup analyses were performed to explore potential causes of heterogeneity. The pooled intraclass correlation coefficients (ICCs) for interobserver and intraobserver reliability were calculated using the Hedges-Olkin method with Fisher's Z transformation of the correlation coefficient. Results: The search yielded 34 articles. From 20 2D-SWE studies including 6196 patients, the pooled proportion of technical failure was 2.3% (95% confidence interval [CI], 1.3-3.9%). The pooled proportion of unreliable measurements from 20 studies including 6961 patients was 7.5% (95% CI, 4.7-11.7%). In the subgroup analyses, studies conducting more than three measurements showed fewer unreliable measurements than did those with three measurements or less, but no intergroup difference was found in technical failure. The pooled ICCs for interobserver reliability (from 10 studies including 517 patients) and intraobserver reliability (from 7 studies including 679 patients) were 0.87 (95% CI, 0.82-0.90) and 0.93 (95% CI, 0.89-0.95), respectively, suggesting good to excellent reliability. Conclusion: 2D-SWE shows good technical performance for assessing liver stiffness, with high technical success and reliability. Future studies should establish the quality criteria and optimal number of measurements.

引用

页码：880 / 893

页数：14

共 60 条

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