Molecular Diversity of Hydroxamic Acids: Part I. Solution- and Solid-Phase Synthesis

被引:20
|
作者
Yang, Kexin [1 ]
Lou, Boliang [1 ]
机构
[1] Adv SynTech, 9800 Bluegrass Pkwy, Louisville, KY 40299 USA
关键词
D O I
10.2174/1389557033488114
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Hydroxamic acid derivatives are an important class of molecules with a variety of pharmaceutical properties. Over the last decade steady progress has been made in the development of efficient methods for the syntheses of hydroxamic acid derivatives. This mini-review covers the most recent publications that highlight current strategies and syntheses of bioactive molecules containing the hydroxamate moiety in both solution-and solid-phase.
引用
收藏
页码:349 / 360
页数:12
相关论文
共 50 条
  • [21] Solution- and solid-phase oligosaccharide synthesis using glucosyl iodides: a comparative study
    Lam, SN
    Gervay-Hague, J
    CARBOHYDRATE RESEARCH, 2002, 337 (21-23) : 1953 - 1965
  • [22] Novel solution- and solid-phase syntheses of heterocyclic systems
    Cabon, G
    Gaucher, B
    Gegout, A
    Heulle, S
    Masquelin, T
    CHIMIA, 2003, 57 (05) : 248 - 254
  • [23] Solution- and solid-phase synthesis of novel hydantoin and isoxazoline-containing heterocycles
    Park, KH
    Abbate, E
    Najdi, S
    Olmstead, MM
    Kurth, MJ
    CHEMICAL COMMUNICATIONS, 1998, (16) : 1679 - 1680
  • [24] Peptidines: glycine-amidine-based oligomers for solution- and solid-phase synthesis
    Vastl, Julian
    Kartika, Rendy
    Park, Kichul
    Cho, Art E.
    Spiegel, David A.
    CHEMICAL SCIENCE, 2016, 7 (05) : 3317 - 3324
  • [25] N-linked hydroxylamine resin:: Solid-phase synthesis of hydroxamic acids
    Yin, Z
    Low, K
    Lye, P
    SYNTHETIC COMMUNICATIONS, 2005, 35 (23) : 2945 - 2950
  • [26] General methodology for solid-phase synthesis of N-alkyl hydroxamic acids
    Krchnák, V
    Slough, GA
    TETRAHEDRON LETTERS, 2004, 45 (24) : 4649 - 4652
  • [27] Novel solution- and solid-phase strategies for the parallel and combinatorial synthesis of small-molecular-weight compound libraries
    Chucholowski, A
    Masquelin, T
    Obrecht, D
    Stadlwieser, J
    Villalgordo, JM
    CHIMIA, 1996, 50 (11) : 525 - 530
  • [28] Solution- and solid-phase synthesis and anti-HIV activity of maslinic acid derivatives containing amino acids and peptides
    Parra, Andres
    Rivas, Francisco
    Lopez, Pilar E.
    Garcia-Granados, Andres
    Martinez, Antonio
    Albericio, Fernando
    Marquez, Nieves
    Munoz, Eduardo
    BIOORGANIC & MEDICINAL CHEMISTRY, 2009, 17 (03) : 1139 - 1145
  • [29] Solid-phase synthesis and solution structure of bicyclic β-turn peptidomimetics:: diversity at the i position
    Eguchi, M
    Lee, MS
    Stasiak, M
    Kahn, M
    TETRAHEDRON LETTERS, 2001, 42 (07) : 1237 - 1239
  • [30] Phosphoramidate-peptide synthesis by solution- and solid-phase Staudinger-phosphite reactions
    Serwa, Remigiusz A.
    Swiecicki, Jean-Marie
    Homann, Denise
    Hackenberger, Christian P. R.
    JOURNAL OF PEPTIDE SCIENCE, 2010, 16 (10) : 563 - 567