Fluorescence Probe Enhanced Spectrofluorimetric Method for the Determination of Prulifloxacin in Pharmaceutical Formulations and Biological Fluids

被引：3

作者：

Yu, Fengshan ^{[1
,2
]}

Gao, Yongwei ^{[1
,3
]}

Cui, Man ^{[1
,4
]}

Chen, Fang ^{[1
,2
]}

Ding, Yanbin ^{[1
,5
]}

机构：

[1] Xuzhou Haotong New Mat Sci & Stock Co Ltd, Dept Inspect & Testing Ctr, Xuzhou 221004, Peoples R China

[2] Huazhong Univ Sci & Technol, Hubei Key Lab Bioinorgan Chem & Mat Med, Coll Chem & Chem Engn, Wuhan 430074, Peoples R China

[3] Jiangsu Polytech Univ, Dept Chem Engn, Changzhou, Peoples R China

[4] Anhui Univ, Sch Chem & Chem Engn, Hefei, Peoples R China

[5] Huaibei Coal Ind Teachers Coll, Coll Chem & Mat Sci, Huaibei, Peoples R China

来源：

ANALYTICAL LETTERS | 2008年 / 41卷 / 16期

基金：

中国国家自然科学基金;

关键词：

Probe; prulifloxacin; spectrofluorimetry; yttrium;

D O I：

10.1080/00032710802440541

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Spectrofluorimetry for the determination of prulifloxacin (PUFX) was developed based on the strong fluorescence of PUFX after adding fluorescence probe yttrium in buffer solution (pH=6.80), and various factors of influencing fluorescence have been researched. Under the optimum conditions, the liner range was 2.010-8 to 9.110-6mol L-1 and the detection limit was 8.510-9mol L-1. The relative standard deviation was 2.1% for 11 measurements of 5.010-7mol L-1 PUFX standard solution. The mechanism of the sensitizing effect of probe was discussed. The method was applied for the determination of PUFX in actual sample; the result obtained was satisfactory.

引用

页码：2933 / 2943

页数：11

共 10 条

[1]

Du LM, 2003, CHINESE J ANAL CHEM, V31, P1330

[2] Determination of the active metabolite of prulifloxacin in human plasma by liquid chromatography-tandem mass spectrometry [J].