Obesity and the Cardiorenal Metabolic Syndrome: Therapeutic Modalities and Their Efficacy in Improving Cardiovascular and Renal Risk Factors

被引：19

作者：

Jindal, Ankur ^{[1
]}

Brietzke, Stephen ^{[1
]}

Sowers, James R. ^{[1
,2
,3
]}

机构：

[1] Univ Missouri, Columbia Sch Med, Dept Internal Med, Columbia, MO 65212 USA

[2] Univ Missouri, Columbia Sch Med, Dept Med Pharmacol & Physiol, Columbia, MO 65212 USA

[3] Harry S Truman VA Med Ctr, Columbia, MO USA

来源：

CARDIORENAL MEDICINE | 2012年 / 2卷 / 04期

关键词：

Obesity; Cardiorenal metabolic syndrome; Cardiovascular disease; Kidney; LOW-FAT DIET; CONTROLLED-RELEASE PHENTERMINE/TOPIRAMATE; BODY-MASS INDEX; WEIGHT-LOSS; LOW-CARBOHYDRATE; BARIATRIC SURGERY; OVERWEIGHT ADULTS; RANDOMIZED-TRIAL; MEDICAL THERAPY; BLOOD-PRESSURE;

D O I：

10.1159/000343803

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The prevalence of obesity has increased rapidly in the United States. Obesity affects about one third of the adult population and, even though it is attributed to excess calorie intake and inadequate physical activity, its etiopathogenesis is much more complex and is an area of active study. Lifestyle modifications (with a focus on increased activity and decreased calorie intake) have modest efficacy in the treatment of obesity. There is a dearth of safe and effective therapeutic modalities to treat obesity. In this review, we discuss the role of different treatment options in the management of obesity and its comorbidities, with a focus on recently approved drugs and the emerging role of bariatric surgery. Copyright (C) 2012 S. Karger AG, Basel

引用

页码：314 / 327

页数：14

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