A Congested in,in-Diphosphine

被引：15

作者：

Zong, Jie ^{[1
]}

Mague, Joel T. ^{[1
]}

Kraml, Christina M. ^{[2
]}

Pascal, Robert A., Jr. ^{[1
]}

机构：

[1] Tulane Univ, Dept Chem, New Orleans, LA 70118 USA

[2] Lotus Separat LLC, Princeton, NJ 08544 USA

来源：

ORGANIC LETTERS | 2013年 / 15卷 / 09期

基金：

美国国家科学基金会;

关键词：

BRIDGEHEAD; CYCLOPHANES; HYDROGEN; ISOMERS;

D O I：

10.1021/ol400728m

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis and characterization of the bis(triarylphosphine) 3 are described. Slow protonation of an inwardly directed phosphine is possible, but the phosphines do not react with larger reagents. X-ray structures of the parent compound, its HCl salt, and the corresponding trisulfone are reported. Compound 3 was resolved by chiral chromatography, but the barrier to racemization is only 20.7 kcal/mol.

引用

收藏

页码：2179 / 2181

页数：3

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