Phosphorylation of aminomalonates

被引：9
作者：
Egorova, A. V. [1 ,2 ]
Viktorov, N. B. [1 ]
Lyamenkova, D. V. [1 ]
Svintsitskaya, N. I. [1 ]
Garabadziu, A. V. [1 ]
Dogadina, A. V. [1 ]
机构：
[1] St Petersburg State Inst Technol Tech Univ, Moskovskii Pr 26, St Petersburg 190013, Russia
[2] Russian Acad Sci, Sci Res Ctr Ecol Safety, St Petersburg, Russia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2016年 / 86卷 / 11期
基金：
俄罗斯基础研究基金会;
关键词：
chloroacetylenephosphonates; aminomalonates; nucleophilic substitution; ENANTIOMERICALLY ENRICHED 2H-AZIRINES; ASYMMETRIC-SYNTHESIS; NUCLEOPHILIC-SUBSTITUTION; ACETYLENIC CARBON; ACID-DERIVATIVES; PHOSPHONATES; CHLOROACETYLENEPHOSPHONATES; CHEMISTRY; OXIDES;
D O I：
10.1134/S1070363216110086
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The reactions of chloroethynylphosphonates with aromatic secondary aminomalonates occur as classic nucleophilic substitution of chlorine atom at the sp-hybridizied carbon atom to form new phosphorylated 2-arylaminomalonates, diethyl esters of 2-(diethoxyphosphorylethynyl)-2-arylaminomalonic acids. Nonobservance of chemo- and regioselectivity was revealed when using cyclohexyl- and benzylaminomalonates.
引用
收藏
页码：2446 / 2453
页数：8
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