Effect of Opioid Peptides on the Content of LPO Products and Antioxidant Enzyme Activity in the Liver of Rats after Restraint Stress

被引：3
|
作者：
Solin, A. V. [1 ]
Lyashev, Yu. D. [1 ]
机构：
[1] Kursk State Med Univ, Dept Pathophysiol, Minist Hlth & Social Dev Russian Federat, Kursk, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2012年 / 153卷 / 06期
关键词：
opioid peptides; liver; stress; lipid peroxidation;
D O I：
10.1007/s10517-012-1836-z
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Administration of opioid peptides dynorphin A (1-13) and DSLET was followed by a decrease in the stress-induced activation of LPO and increase in SOD activity in the liver tissue of rats. DAGO produced a similar, but less pronounced effect. The observed changes can be related to a specific distribution of opioid receptors in the liver tissue and stress-limiting influence of these peptides in the whole body.
引用
收藏
页码：828 / 830
页数：3
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