Brachytherapy for oesophageal cancer

被引:4
作者
Wong, S. [1 ]
Hennequin, C. [1 ]
Quero, L. [1 ]
机构
[1] Hop St Louis, Serv Cancerol Radiotherapie, F-75475 Paris, France
来源
CANCER RADIOTHERAPIE | 2013年 / 17卷 / 02期
关键词
Brachytherapy; Oesophageal cancer; High dose-rate; EXTERNAL-BEAM RADIATION; DOSE-RATE BRACHYTHERAPY; MULTICENTER RANDOMIZED-TRIAL; ATOMIC-ENERGY-AGENCY; INTRALUMINAL BRACHYTHERAPY; STENT PLACEMENT; CARCINOMA; PALLIATION; THERAPY; CHEMOTHERAPY;
D O I
10.1016/j.canrad.2013.03.003
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The main indication of oesophageal brachytherapy is palliative: it can improve dysphagia in patients with a tumor not suitable for surgery or chemoradiotherapy. A randomized clinical trial showed that survival without dysphagia and quality of life was improved by endoluminal brachytherapy in comparison to self-expansible metallic stents. It also increases the duration of palliation after laser deobstruction. Its role as a curative treatment of locally advanced tumors is still discussed: in combination with external beam radiotherapy, it seems that brachytherapy increased the rate of severe toxicity (haemorrhages, fistula, stenosis). In superficial lesions, brachytherapy with or without external beam radiotherapy seems logical but large prospective studies are missing in this setting. (C) 2013 Published by Elsevier Masson SAS on behalf of the Societe francaise de radiotherapie oncologique (SFRO).
引用
收藏
页码:159 / 161
页数:3
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