Production, Secretion and Biological Activity of Bacillus cereus Enterotoxins

被引：91

作者：

Senesi, Sonia ^{[1
]}

Ghelardi, Emilia ^{[2
]}

机构：

[1] Univ Pisa, Dipartimento Biol, I-56127 Pisa, Italy

[2] Univ Pisa, Dipartimento Patol Sperimentale Biotecnol Med Inf, I-56127 Pisa, Italy

来源：

TOXINS | 2010年 / 2卷 / 07期

关键词：

hemolysin BL; non-hemolytic enterotoxin; cytotoxin K; B; cereus; TRIPARTITE HEMOLYSIN BL; FLAGELLAR EXPORT APPARATUS; PLCR VIRULENCE REGULON; RAY CRYSTAL-STRUCTURE; PROTEIN-SECRETION; GENE-EXPRESSION; BROAD DISTRIBUTION; ANTHRACIS; TOXIN; COMPONENTS;

D O I：

10.3390/toxins2071690

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Bacillus cereus behaves as an opportunistic pathogen frequently causing gastrointestinal diseases, and it is increasingly recognized to be responsible for severe local or systemic infections. Pathogenicity of B. cereus mainly relies on the secretion of a wide array of toxins and enzymes and also on the ability to undergo swarming differentiation in response to surface-sensing. In this report, the pathogenicity exerted by B. cereus toxins is described with particular attention to the regulatory mechanisms of production and secretion of HBL, Nhe and CytK enterotoxins.

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页码：1690 / 1703

页数：14

相关论文

共 73 条

[41] A new cytotoxin from Bacillus cereus that may cause necrotic enteritis [J].

Lund, T ;

De Buyser, ML ;

Granum, PE .

MOLECULAR MICROBIOLOGY, 2000, 38 (02) :254-261

[42] The 105-kDa protein component of Bacillus cereus non-haemolytic enterotoxin (Nhe) is a metalloprotease with gelatinolytic and collagenolytic activity [J].

Lund, T ;

Granum, PE .

FEMS MICROBIOLOGY LETTERS, 1999, 178 (02) :355-361

[43]

Lund T, 1996, FEMS MICROBIOL LETT, V141, P151, DOI 10.1016/0378-1097(96)00208-X

[44]

Macnab R.M., 1996, ESCHERICHIA COLI SAL, P123

[45] X-ray crystal structure of the B component of Hemolysin BL from Bacillus cereus [J].

Madegowda, Mahendra ;

Eswaramoorthy, Subramaniam ;

Burley, Stephen K. ;

Swaminathan, Subramanyam .

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2008, 71 (02) :534-540

[46] Identification of Bacillus cereus Group Species Associated with Food Poisoning Outbreaks in British Columbia, Canada [J].

McIntyre, Lorraine ;

Bernard, Kathryn ;

Beniac, Daniel ;

Isaac-Renton, Judith L. ;

Naseby, David Craig .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2008, 74 (23) :7451-7453

[47] Fnr mediates carbohydrate-dependent regulation of catabolic and enterotoxin genes in Bacillus cereus F4430/73 [J].

Messaoudi, Kahina ;

Clavel, Thierry ;

Schmitt, Philippe ;

Duport, Catherine .

RESEARCH IN MICROBIOLOGY, 2010, 161 (01) :30-39

[48] The incompatibility between the PlcR- and AtxA-controlled regulons may have selected a nonsense mutation in Bacillus anthracis [J].

Mignot, T ;

Mock, M ;

Robichon, D ;

Landier, A ;

Lereclus, D ;

Fouet, A .

MOLECULAR MICROBIOLOGY, 2001, 42 (05) :1189-1198

[49] Components of the Salmonella flagellar export apparatus and classification of export substrates [J].

Minamino, T ;

Macnab, RM .

JOURNAL OF BACTERIOLOGY, 1999, 181 (05) :1388-1394

[50] Determination of the toxic potential of Bacillus cereus isolates by quantitative enterotoxin analyses [J].

Moravek, M ;

Dietrich, R ;

Buerk, C ;

Broussolle, V ;

Guinebretière, MH ;

Granum, PE ;

Nguyen-the, C ;

Märtlbauer, E .

FEMS MICROBIOLOGY LETTERS, 2006, 257 (02) :293-298

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