Production, Secretion and Biological Activity of Bacillus cereus Enterotoxins

被引：91

作者：

Senesi, Sonia ^{[1
]}

Ghelardi, Emilia ^{[2
]}

机构：

[1] Univ Pisa, Dipartimento Biol, I-56127 Pisa, Italy

[2] Univ Pisa, Dipartimento Patol Sperimentale Biotecnol Med Inf, I-56127 Pisa, Italy

来源：

TOXINS | 2010年 / 2卷 / 07期

关键词：

hemolysin BL; non-hemolytic enterotoxin; cytotoxin K; B; cereus; TRIPARTITE HEMOLYSIN BL; FLAGELLAR EXPORT APPARATUS; PLCR VIRULENCE REGULON; RAY CRYSTAL-STRUCTURE; PROTEIN-SECRETION; GENE-EXPRESSION; BROAD DISTRIBUTION; ANTHRACIS; TOXIN; COMPONENTS;

D O I：

10.3390/toxins2071690

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Bacillus cereus behaves as an opportunistic pathogen frequently causing gastrointestinal diseases, and it is increasingly recognized to be responsible for severe local or systemic infections. Pathogenicity of B. cereus mainly relies on the secretion of a wide array of toxins and enzymes and also on the ability to undergo swarming differentiation in response to surface-sensing. In this report, the pathogenicity exerted by B. cereus toxins is described with particular attention to the regulatory mechanisms of production and secretion of HBL, Nhe and CytK enterotoxins.

引用

页码：1690 / 1703

页数：14

共 73 条

[1] PlcR is a pleiotropic regulator of extracellular virulence factor gene expression in Bacillus thuringiensis [J].