Wound Coverage Technologies in Burn Care: Novel Techniques

被引:31
作者
Jeschke, Marc G. [1 ,2 ,3 ,4 ,5 ]
Finnerty, Celeste C. [2 ]
Shahrokhi, Shahriar [2 ]
Branski, Ludwik K. [6 ]
Dibildox, Manuel [2 ]
机构
[1] Univ Toronto, Toronto, ON M4N 3M5, Canada
[2] Univ Texas Med Branch, Dept Surg, Div Plast Surg, Galveston, TX 77555 USA
[3] Univ Texas Med Branch, Dept Immunol, Galveston, TX 77555 USA
[4] Univ Texas Med Branch, Sunnybrook Hlth Sci Ctr, Ross Tilley Burn Ctr, Galveston, TX 77555 USA
[5] Univ Texas Med Branch, Sunnybrook Res Inst, Galveston, TX 77555 USA
[6] Hannover Med Sch, Dept Plast & Reconstruct Surg, Hannover, Germany
基金
美国国家卫生研究院; 加拿大健康研究院;
关键词
CULTURED SKIN SUBSTITUTES; ENDOTHELIAL GROWTH-FACTOR; LIPOSOMAL GENE-TRANSFER; STEM-CELL THERAPY; FIBRIN SEALANT; IGF-I; ELECTRICAL-STIMULATION; EPIDERMAL REGENERATION; ADENOVIRUS VECTORS; PARTIAL-THICKNESS;
D O I
10.1097/BCR.0b013e31829b0075
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Improvements in burn wound care have vastly decreased morbidity and mortality in severely burned patients. Development of new therapeutic approaches to increase wound repair has the potential to reduce infection, graft rejection, and hypertrophic scarring. The incorporation of tissue-engineering techniques, along with the use of exogenous proteins, genes, or stem cells to enhance wound healing, heralds new treatment regimens based on the modification of already existing biological activity. Refinements to surgical techniques have enabled the creation of protocols for full facial transplantation. With new technologies and advances such as these, care of the severely burned will undergo massive changes over the next decade. This review centers on new developments that have recently shown great promise in the investigational arena.
引用
收藏
页码:612 / 620
页数:9
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