The laboratories are an important part in university because the quality of the facilities and their management of the laboratories would directly affect the quality of teaching and research of the institution. The functional modules have been developed, based on a functional analysis of the characteristics and actual situation of the laboratory management, using a Web-based, object-oriented and modulated designing approach, namely, the system management, the lab-teaching management, the lab-information management, research information management, and the file management modules, which are made into Web-based laboratory management information system that combines the B/S and the C/S modes. Test shows that the system meets the final proposed foals.