Application of chitosan matrix for delivery of rutin

被引:9
作者
Queiroz de Arruda, Iza Natalia [1 ]
Pereira, Valdir Aniceto, Jr. [1 ]
Stefani, Ricardo [1 ]
机构
[1] UFMT, Mat Res Lab LEMat, Campus Univ Araguaia,BR-070,Km 5, BR-78600000 Barra Do Garcas, MT, Brazil
关键词
Chitosan; Controlled release; Smart polymers; Flavonoids; SUBMICRON PARTICLES; CONTROLLED-RELEASE; FILMS; HYDROGELS; PRECIPITATION; NANOPARTICLES; ENCAPSULATION; ANTIOXIDANTS; FLAVONOIDS; MICELLES;
D O I
10.1007/s13738-016-1004-x
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Chitosan matrices are an alternative material to the food industry, due to its ability to release bioactive compounds through interconnected cavities. Chitosan is a biomaterial of excellence, because it shows unique features, such as biocompatibility, non-toxicity, bactericidal action and the ability to associate with other compounds. Thus, this study aimed the development of chitosan matrices incorporated with rutin, as well as the evaluation of rutin release. Chitosan matrices with rutin were prepared by the coacervation method in alkaline solution and subsequently characterized through FT-IR, TG-DSC, X-ray diffraction, SEM and further submitted to rutin release assay. Results show the effectiveness in the incorporation of rutin into the polymeric matrix. The polymeric matrix with rutin can quickly release it, which provides a wide range of applications, such as carrier of rutin as a micronutrient food additive.
引用
收藏
页码:561 / 566
页数:6
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