Vascular endothelial growth factor in reproductive biology

被引：24

作者：

Lebovic, DI ^{[1
]}

Mueller, MD ^{[1
]}

Taylor, RN ^{[1
]}

机构：

[1] Univ Calif San Francisco, Ctr Reprod Endocrinol, Dept Obstet Gynecol & Reprod Sci, San Francisco, CA 94143 USA

来源：

CURRENT OPINION IN OBSTETRICS & GYNECOLOGY | 1999年 / 11卷 / 03期

关键词：

D O I：

10.1097/00001703-199906000-00004

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The critical role of angiogenesis in embryology and tumor biology has been recognized for more than 20 years. However, the fact that neovascularization is essential to processes in mammalian female reproduction has only recently been appreciated widely. In this review we focus on a single angiogenic growth factor, vascular endothelial growth factor. As scientists have discovered in many aspects of cell biology, multiple and redundant signaling pathways have evolved in nature, presumably to protect essential biological functions from inactivating diseases or mutations. Despite this redundancy, some factors are of hierarchical importance. Vascular endothelial growth factor appears to be such a factor in the regulation of angiogenesis. (C) 1999 Lippincott Williams & Wilkins.

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收藏

页码：255 / 260

页数：6

相关论文

共 54 条

[11] IDENTIFICATION AND LOCALIZATION OF ALTERNATELY SPLICED MESSENGER-RNAS FOR VASCULAR ENDOTHELIAL GROWTH-FACTOR IN HUMAN UTERUS AND ESTROGEN REGULATION IN ENDOMETRIAL CARCINOMA CELL-LINES [J].

CHARNOCKJONES, DS ;

SHARKEY, AM ;

RAJPUTWILLIAMS, J ;

BURCH, D ;

SCHOFIELD, JP ;

FOUNTAIN, SA ;

BOOCOCK, CA ;

SMITH, SK .

BIOLOGY OF REPRODUCTION, 1993, 48 (05) :1120-1128

[12]

Clark DE, 1996, HUM REPROD, V11, P1090

[13] VEGF mRNA levels in placentae from pregnancies complicated by pre-eclampsia [J].

Cooper, JC ;

Sharkey, AM ;

CharnockJones, DS ;

Palmer, CR ;

Smith, SK .

BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1996, 103 (12) :1191-1196

[14] VASCULAR ENDOTHELIAL GROWTH-FACTOR VASCULAR-PERMEABILITY FACTOR EXPRESSION IN THE RAT UTERUS - RAPID STIMULATION BY ESTROGEN CORRELATES WITH ESTROGEN-INDUCED INCREASES IN UTERINE CAPILLARY-PERMEABILITY AND GROWTH [J].

CULLINANBOVE, K ;

KOOS, RD .

ENDOCRINOLOGY, 1993, 133 (02) :829-837

[15]

Dlugi AM, 1998, FERTIL STERIL, V70, P253

[16] In controlled ovarian hyperstimulation, steroid production, oocyte retrieval, and pregnancy rate correlate with gene expression of vascular endothelial growth factor [J].

Doldi, N ;

Bassan, M ;

Fusi, FM ;

Ferrari, A .

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, 1997, 14 (10) :589-592

[17] Vascular endothelial growth factor (VEGF) in endometriosis [J].

Donnez, J ;

Smoes, P ;

Gillerot, S ;

Casanas-Roux, F ;

Nisolle, M .

HUMAN REPRODUCTION, 1998, 13 (06) :1686-1690

[18] DIRECT ARTERIAL VASCULARIZATION OF ESTROGEN-INDUCED PROLACTIN-SECRETING ANTERIOR-PITUITARY TUMORS [J].

ELIAS, KA ;

WEINER, RI .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (14) :4549-4553

[19] A longitudinal study of maternal serum vascular endothelial growth factor in early pregnancy [J].

Evans, PW ;

Wheeler, T ;

Anthony, FW ;

Osmond, C .

HUMAN REPRODUCTION, 1998, 13 (04) :1057-1062

[20] Vascular endothelial growth factor is essential for corpus luteum angiogenesis [J].

Ferrara, N ;

Chen, H ;

Davis-Smyth, T ;

Gerber, HP ;

Nguyen, TN ;

Peers, D ;

Chisholm, V ;

Hillan, KJ ;

Schwall, RH .

NATURE MEDICINE, 1998, 4 (03) :336-340

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