Thionation of esters and lactones with the reagent combination of phosphorus pentasulfide and hexamethyldisiloxane

被引：41
作者：
Curphey, TJ [1 ]
机构：
[1] Dartmouth Coll Sch Med, Dept Pathol, Hanover, NH 03755 USA
来源：
TETRAHEDRON LETTERS | 2002年 / 43卷 / 03期
基金：
美国国家科学基金会;
关键词：
thioesters; thiocarbonyl compounds; thiophosphates; silicon and compounds;
D O I：
10.1016/S0040-4039(01)02144-X
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The combination of P4S10 and hexamethyldisiloxane converts esters and lactones to thionoesters and thionolactones in yields comparable to or superior to those obtained with Lawesson's reagent. The method has the advantage that reagent-derived byproducts may be removed by a simple hydrolytic workup or by filtration through silica gel, rather than by chromatography, as required for Lawesson's reagent. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：371 / 373
页数：3
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