Effect of Probiotic Lactobacillus Strains on Angiotensin I Converting Enzyme Inhibitory Activity from Fermented Goat Milk

被引：15

作者：

Chen, He ^{[1
]}

Ji, Zhe ^{[1
]}

Shu, Guowei ^{[1
]}

Xing, Hongni ^{[1
]}

机构：

[1] Shaanxi Univ Sci & Technol, Coll Life Sci & Engn, Xian, Peoples R China

来源：

ADVANCED RESEARCH ON MATERIAL ENGINEERING, CHEMISTRY, BIOINFORMATICS II | 2012年 / 531卷

关键词：

ACE inhibitory peptide; probiotic Lactobacillus; fermented goat milk; PEPTIDES;

D O I：

10.4028/www.scientific.net/AMR.531.442

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Goat milk was fermented by different strains of lactic acid bacterias in anaerobic tube, strains with high angiotensin converting enzyme (ACE) inhibitory activity were screened from 28 probiotic Lactobacillus strains by the criteria of ACE inhibitory activity and pH. The results showed that 20 strains had ACE inhibitory activity and among them the activity of 4 strains were extremely high, they were Lactobacillus reuteri, Lactobacillus bulgaricus, Lactobacillus rhamnosu and Lactobacillus helveticu. In vitro experiments, the ACE inhibitory activity of goat milk fermented by these 4 strains reached 95.92%, 84.61%, 82.79% and 78.57%, respectively. After incubation, pH of them were 6.17, 3.88, 5.24 and 3.71, respectively.

引用

页码：442 / 445

页数：4

共 7 条

[1] Milk fermentation by Lactococcus lactis with modified proteolytic systems to accumulate potentially bio-active peptides [J].

Algaron, F ;

Miranda, G ;

Le Bars, D ;

Monnet, V .

LAIT, 2004, 84 (1-2) :115-123

[2]

Ashar MN, 2004, MILCHWISSENSCHAFT, V59, P14

[3] Latent bioactive peptides in milk proteins: Proteolytic activation and significance in dairy processing [J].

Gobetti, M ;

Stepaniak, L ;

De Angelis, M ;

Corsetti, A ;

Di Cagno, R .

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, 2002, 42 (03) :223-239

[4] Production of angiotensin-I-converting enzyme (ACE) inhibitory activity in milk fermented with probiotic strains: Effects of calcium, pH and peptides on the ACE-inhibitory activity [J].

Gonzalez-Gonzalez, C. R. ;

Tuohy, K. M. ;

Jauregi, P. .

INTERNATIONAL DAIRY JOURNAL, 2011, 21 (09) :615-622

[5] Angiotensin I-converting enzyme inhibitory activity in milk fermented by wild-type and peptidase-deletion derivatives of Lactobacillus helveticus CNRZ32 [J].

Kilpi, E. E. -R. ;

Kahala, M. M. ;

Steele, J. L. ;

Pihlanto, A. M. ;

Joutsjoki, V. V. .

INTERNATIONAL DAIRY JOURNAL, 2007, 17 (08) :976-984

[6] Angiotensin I-converting-enzyme-inhibitory and antibacterial peptides from Lactobacillus helveticus PR4 proteinase-hydrolyzed caseins of milk from six species [J].

Minervini, F ;

Algaron, F ;

Rizzello, CG ;

Fox, PF ;

Monnet, V ;

Gobbetti, A .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2003, 69 (09) :5297-5305

[7] Angiotensin-converting enzyme inhibitory activity of peptides derived from caprine kefir [J].

Quirós, A ;

Hernández-Ledesma, B ;

Ramos, M ;

Amigo, L ;

Recio, I .

JOURNAL OF DAIRY SCIENCE, 2005, 88 (10) :3480-3487

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