Three-Dimensional Photonic Structures on Transparent Substrates Fabricated by Two-Photon Polymerization for Use as Cell Substrates and for Wetting Experiments

被引：0

作者：

Heitz, Johannes ^{[1
]}

Plamadeala, Cristina ^{[1
]}

Wiesbauer, Moritz ^{[1
]}

Freudenthaler, Peter ^{[1
]}

Wollhofen, Richard ^{[1
]}

Jacak, Jaroslaw ^{[1
]}

Puthukodan, Sujitha ^{[1
]}

Klar, Thomas A. ^{[1
]}

Weth, Agnes ^{[2
]}

Baumgartner, Werner ^{[2
]}

Magnus, Birte ^{[3
]}

Marksteiner, Rainer ^{[1
,3
]}

机构：

[1] Johannes Kepler Univ Linz, Inst Appl Phys, A-4040 Linz, Austria

[2] Johannes Kepler Univ Linz, Inst Biomed Mechatron, A-4040 Linz, Austria

[3] Innovacell Biotechnol AG, A-6020 Innsbruck, Austria

来源：

2016 18TH INTERNATIONAL CONFERENCE ON TRANSPARENT OPTICAL NETWORKS (ICTON) | 2016年

关键词：

three-dimensional photonic micro- and nanostructures; two-photon polymerization; biological cells; wetting experiments; biomimetics;

D O I：

暂无

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Polymer micro-and nanostructures with various geometries can be written onto a transparent substrate by the technique of two-photon polymerization by a Ti-sapphire femtosecond-laser, which is focused into a liquid acrylate based resin containing a photo-initiator. The microstructures can be employed either as three-dimensional tissue scaffold onto which adherent cells can be seeded or are used as topological substrates for wetting experiments. Due to confinement to the microstructures and/or mechanical interaction with the scaffold, skin derived cells can be stimulated to grow three-dimensionally and to produce calcium binding proteins. The periodic laser-written structures may have other potential applications in the field of bio-inspired microfluidic devices due to their good wettability and water sustainment.

引用

页数：4

共 5 条

[1] VUV treatment combined with mechanical strain of stretchable polymer foils resulting in cell alignment [J].