Palladium-catalyzed benzylic direct arylation of benzyl sulfones with aryl halides

被引：39
|
作者：
Niwa, Takashi [1 ]
Yorimitsu, Hideki [1 ]
Oshima, Koichiro [1 ]
机构：
[1] Kyoto Univ, Grad Sch Engn, Dept Chem Mat, Nishikyo Ku, Kyoto 6158510, Japan
来源：
TETRAHEDRON | 2009年 / 65卷 / 10期
关键词：
Direct arylation; Palladium catalysis; Diarylmethyl sulfone; INTRAMOLECULAR ALPHA-ARYLATION; C(SP(3))-H BOND ACTIVATION; CONDENSED N-HETEROCYCLES; C-H ACTIVATION; REGIOSELECTIVE ARYLATION; SUBSTITUTION-REACTIONS; CARBONYL-COMPOUNDS; CARBOXYLIC-ACIDS; KETONES; DERIVATIVES;
D O I：
10.1016/j.tet.2009.01.030
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An effective palladium catalyst system for the direct arylation of benzyl sulfones with aryl halides has been developed. The catalytic reaction provides a facile route to diarylmethyl sulfones. The products can be transformed further via desulfonylative functionalization mediated by aluminum compounds. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1971 / 1976
页数：6
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