The latest on skin photoprotection

被引:191
作者
Gonzalez, Salvador [1 ]
Fernandez-Lorente, Manuel [2 ]
Gilaberte-Calzada, Yolanda [3 ]
机构
[1] Mem Sloan Kettering Canc Ctr, Dermatol Serv, New York, NY 10022 USA
[2] Hosp Ramon & Cajal, Dermatol Serv, E-28034 Madrid, Spain
[3] Hosp Gen San Jorge, Dermatol Serv, Huesca 22003, Spain
关键词
D O I
10.1016/j.clindermatol.2007.09.010
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
UV radiation is the main etiological agent of most types of skin cancer and a key factor responsible for photoaging. Photoprotection is thus critical to avoid these undesired effects. Sunscreens rank among the best photoprotective measures. Sunscreens are the main components of lotions and creams used to prevent UV-induced damage or to ameliorate its harmful effects. There are 3 types of sunscreens: physical photon blockers, antioxidants, and stimulators of repairing mechanisms. This review summarizes current topics in the development of sunscreens, with special emphasis on substances of natural origin bearing photoscreening, antioxidant, or repairing properties. The characterization of different parameters to evaluate the effects of sunscreens, such as the sunscreen protection factor, is discussed. Finally, the effect of public awareness and public health campaigns are also reviewed. (C) 2008 Elsevier Inc. All rights reserved.
引用
收藏
页码:614 / 626
页数:13
相关论文
共 140 条
[1]   Prevention of short-term ultraviolet B radiation-mediated damages by resveratrol in SKH-1 hairless mice [J].
Afaq, F ;
Adhami, VM ;
Ahmad, N .
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2003, 186 (01) :28-37
[2]   Botanical antioxidants in the prevention of photocarcinogenesis and photoaging [J].
Afaq, Farrukh ;
Mukhtar, Hasan .
EXPERIMENTAL DERMATOLOGY, 2006, 15 (09) :678-684
[3]  
Al Mahroos M, 2002, ARCH DERMATOL, V138, P1480
[4]   An extract of Polypodium leucotomos appears to minimize certain photoaging changes in a hairless albino mouse animal model -: A pilot study [J].
Alcaraz, MV ;
Pathak, MA ;
Rius, F ;
Kollias, N ;
González, S .
PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE, 1999, 15 (3-4) :120-126
[5]   Photoprotective properties of a hydrophilic extract of the fern Polypodium leucotomos on human skin cells [J].
Alonso-Lebrero, JL ;
Domínguez-Jiménez, C ;
Tejedor, R ;
Brieva, A ;
Pivel, JP .
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 2003, 70 (01) :31-37
[6]   T-oligos augment UV-induced protective responses in human skin [J].
Arad, Simin ;
Konnikov, Nellie ;
Goukassian, David A. ;
Gilchrest, Barbara A. .
FASEB JOURNAL, 2006, 20 (11) :1895-+
[7]   Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease? [J].
Aziz, MH ;
Reagan-Shaw, S ;
Wu, JQ ;
Longley, BJ ;
Ahmad, N .
FASEB JOURNAL, 2005, 19 (06) :1193-+
[8]   Singlet oxygen mediates the UVA-induced generation of the photoaging-associated mitochondrial common deletion [J].
Berneburg, M ;
Grether-Beck, S ;
Kürten, V ;
Ruzicka, T ;
Briviba, K ;
Sies, H ;
Krutmann, J .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (22) :15345-15349
[9]  
Bernerd F, 2000, PHOTOCHEM PHOTOBIOL, V71, P314, DOI 10.1562/0031-8655(2000)071<0314:EOTPEO>2.0.CO
[10]  
2