Per-6-amino-β-cyclodextrin as an Efficient Supramolecular Ligand and Host for Cu(I)-Catalyzed N-Arylation of Imidazole with Aryl Bromides

被引：86

作者：

Suresh, Palaniswamy ^{[1
]}

Pitchumani, Kasi ^{[1
]}

机构：

[1] Madurai Kamaraj Univ, Sch Chem, Madurai 625021, Tamil Nadu, India

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2008年 / 73卷 / 22期

关键词：

D O I：

10.1021/jo801811w

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Per-6-amino-beta-cyclodextrin (per-6-ABCD), acting simultaneously as a supramolecular ligand for CuI and host for aryl bromides, catalyzes N-arylation of imidazole with aryl bromides under mild conditions. This simple method proceeds with excellent yield for the coupling of imidazole with various substituted aryl bromides demonstrating good tolerance of other functionalities.

引用

页码：9121 / 9124

页数：4

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