ERS/ATS workshop report on respiratory health effects of household air pollution

被引:78
作者
Sood, Akshay [1 ]
Assad, Nour A. [1 ]
Barnes, Peter J. [2 ]
Churg, Andrew [3 ]
Gordon, Stephen B. [4 ]
Harrod, Kevin S. [5 ]
Irshad, Hammad [6 ]
Kurmi, Om P. [7 ]
Martin, William J., II [8 ]
Meek, Paula [9 ]
Mortimer, Kevin [4 ]
Noonan, Curtis W. [10 ]
Perez-Padilla, Rogelio [11 ]
Smith, Kirk R. [12 ]
Tesfaigzi, Yohannes [6 ]
Ward, Tony [10 ]
Balmes, John [12 ,13 ]
机构
[1] Univ New Mexico, Sch Med, Albuquerque, NM 87131 USA
[2] Imperial Coll London, Natl Heart & Lung Inst, London, England
[3] Univ British Columbia, Vancouver, BC, Canada
[4] Univ Liverpool Liverpool Sch Trop Med, Liverpool, Merseyside, England
[5] Univ Alabama Birmingham, Birmingham, AL USA
[6] Lovelace Resp Res Inst, Albuquerque, NM USA
[7] Univ Oxford, Oxford, England
[8] Ohio State Univ, Columbus, OH 43210 USA
[9] Univ Colorado, Denver, CO 80202 USA
[10] Univ Montana, Missoula, MT 59812 USA
[11] Inst Nacl Enfermedades Resp, Mexico City, DF, Mexico
[12] Univ Calif Berkeley, Sch Publ Hlth, Berkeley, CA 94720 USA
[13] Univ Calif San Francisco, San Francisco, CA 94143 USA
关键词
OBSTRUCTIVE PULMONARY-DISEASE; LUNG-FUNCTION GROWTH; WOOD SMOKE EXPOSURE; COMPARATIVE RISK-ASSESSMENT; LONG-TERM EXPOSURE; BIOMASS SMOKE; PARTICULATE MATTER; CARBON-MONOXIDE; OXIDATIVE STRESS; GLOBAL BURDEN;
D O I
10.1183/13993003.00698-2017
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Exposure to household air pollution (HAP) from solid fuel combustion affects almost half of the world population. Adverse respiratory outcomes such as respiratory infections, impaired lung growth and chronic obstructive pulmonary disease have been linked to HAP exposure. Solid fuel smoke is a heterogeneous mixture of various gases and particulates. Cell culture and animal studies with controlled exposure conditions and genetic homogeneity provide important insights into HAP mechanisms. Impaired bacterial phagocytosis in exposed human alveolar macrophages possibly mediates several HAP-related health effects. Lung pathological findings in HAP-exposed individuals demonstrate greater small airways fibrosis and less emphysema compared with cigarette smokers. Field studies using questionnaires, air pollution monitoring and/or biomarkers are needed to better establish human risks. Some, but not all, studies suggest that improving cookstove efficiency or venting emissions may be associated with reduced respiratory symptoms, lung function decline in women and severe pneumonia in children. Current studies focus on fuel switching, stove technology replacements or upgrades and air filter devices. Several governments have initiated major programmes to accelerate the upgrade from solid fuels to clean fuels, particularly liquid petroleum gas, which provides research opportunities for the respiratory health community.
引用
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页数:14
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