Familial clustering of intracerebral hemorrhage: A prospective study in north Carolina

被引：22

作者：

Alberts, MJ ^{[1
]}

McCarron, MO ^{[1
]}

Hoffmann, KL ^{[1
]}

Graffagnino, C ^{[1
]}

机构：

[1] Duke Univ, Med Ctr, Dept Med, Div Neurol, Durham, NC 27710 USA

来源：

NEUROEPIDEMIOLOGY | 2002年 / 21卷 / 01期

关键词：

intracerebral hemorrhage; familial clustering;

D O I：

10.1159/000048609

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Few studies have assessed the frequency of familial clustering in intracerebral hemorrhage (ICH). Of 144 patients with ICH prospectively assessed, 14 (9.8%) had a positive family history of ICH (FH+). Four pedigrees had more than two affected family members. Comparisons between FH+ and FH- probands demonstrated no significant differences in race, age, sex, ICH type or location. An underlying genetic etiology may account for familial clustering in some ICH patients. Copyright (C) 2002 S. Karger AG, Basel.

引用

页码：18 / 21

页数：4

共 10 条

[1] Endoglin gene polymorphism as a risk factor for sporadic intracerebral hemorrhage [J].

Alberts, MJ ;

Davis, JP ;

Graffagnino, C ;

McClenny, C ;

DeLong, D ;

Granger, C ;

Herbstreith, MH ;

Boteva, K ;

Marchuk, DA ;

Roses, AD .

ANNALS OF NEUROLOGY, 1997, 41 (05) :683-686

[2] A MOLECULAR-GENETIC STUDY OF INTRACEREBRAL HEMORRHAGE [J].

GRAFFAGNINO, C ;

HERBSTREITH, MH ;

ROSES, AD ;

ALBERTS, MJ .

ARCHIVES OF NEUROLOGY, 1994, 51 (10) :981-984

[3] APOLIPOPROTEIN-E EPSILON-4 AND CEREBRAL-HEMORRHAGE ASSOCIATED WITH AMYLOID ANGIOPATHY [J].

GREENBERG, SM ;

REBECK, GW ;

VONSATTEL, JPG ;

GOMEZISLA, T ;

HYMAN, BT .

ANNALS OF NEUROLOGY, 1995, 38 (02) :254-259

[4] Parental history of cardiovascular disease and risk of stroke - A prospective follow-up of 14,371 middle-aged men and women in Finland [J].

Jousilahti, P ;

Rastenyte, D ;

Tuomilehto, J ;

Sarti, C ;

Vartiainen, E .

STROKE, 1997, 28 (07) :1361-1366

[5] Is family history an independent risk factor for stroke? [J].

Kubota, M ;

Yamaura, A ;

Ono, J ;

Itani, T ;

Tachi, N ;

Ueda, K ;

Nagata, I ;

Sugimoto, S .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1997, 62 (01) :66-70

[6] Familial Incidence of Cerebral Hemorrhage [J].

Marshall, John .

STROKE, 1973, 4 (01) :38-41

[7] High frequency of apolipoprotein E epsilon 2 in patients with cerebral hemorrhage due to cerebral amyloid angiopathy [J].

Nicoll, JAR ;

Burnett, C ;

Love, S ;

Graham, DI ;

Ironside, JW ;

Vinters, HV .

ANNALS OF NEUROLOGY, 1996, 39 (05) :682-682

[8]

Taira S, 1994, Nihon Koshu Eisei Zasshi, V41, P1142

[9] Risk factors for cerebral hemorrhage in the era of well-controlled hypertension [J].

Thrift, AG ;

McNeil, JJ ;

Forbes, A ;

Donnan, GA .

STROKE, 1996, 27 (11) :2020-2025

[10]

Woo D, 2000, STROKE, V31, P316

← 1 →