Use of Magnetic Forces to Promote Stem Cell Aggregation During Differentiation, and Cartilage Tissue Modeling

被引:80
作者
Fayol, D. [1 ,2 ]
Frasca, G. [1 ,2 ]
Le Visage, C. [1 ,2 ]
Gazeau, F. [1 ,2 ]
Luciani, N. [1 ,2 ]
Wilhelm, C. [1 ,2 ]
机构
[1] CNRS, Lab Mat & Syst Complexes MSC, UMR 7057, Paris, France
[2] Univ Paris Diderot, Paris, France
关键词
stem cell differentiation; cartilage tissue engineering; magnetic nanoparticles; bionanotechnology; magnetic cell manipulation; IN-VIVO; REGENERATIVE MEDICINE; NANOPARTICLES; CHONDROGENESIS; TRACKING; FERUMOXIDES; RESONANCE; FABRICATION; CLEARANCE; VITRO;
D O I
10.1002/adma.201300342
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Magnetic forces induce cell condensation necessary for stem cell differentiation into cartilage and elicit the formation of a tissue-like structure: Magnetically driven fusion of aggregates assembled by micromagnets results in the formation of a continuous tissue layer containing abundant cartilage matrix. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:2611 / 2616
页数:6
相关论文
共 47 条
[1]   Construction of Cardiac Tissue Rings Using a Magnetic Tissue Fabrication Technique [J].
Akiyama, Hirokazu ;
Ito, Akira ;
Sato, Masanori ;
Kawabe, Yoshinori ;
Kamihira, Masamichi .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2010, 11 (08) :2910-2920
[2]   Dual in vivo magnetic resonance evaluation of magnetically labeled mouse embryonic stem cells and cardiac function at 1.5 T [J].
Arai, T ;
Kofidis, T ;
Bulte, JWM ;
de Bruin, J ;
Venook, RD ;
Berry, GJ ;
Mcconnell, MV ;
Quertermous, T ;
Robbins, RC ;
Yang, PC .
MAGNETIC RESONANCE IN MEDICINE, 2006, 55 (01) :203-209
[3]   Labeling of cells with ferumoxides-protamine sulfate complexes does not inhibit function or differentiation capacity of hematopoietic or mesenchymal stem cells [J].
Arbab, AS ;
Yocum, GT ;
Rad, AM ;
Khakoo, AY ;
Fellowes, V ;
Read, EJ ;
Frank, JA .
NMR IN BIOMEDICINE, 2005, 18 (08) :553-559
[4]   Visualization of cartilage formation: Insight into cellular properties of skeletal progenitors and chondrodysplasia syndromes [J].
Barna, Maria ;
Niswander, Lee .
DEVELOPMENTAL CELL, 2007, 12 (06) :931-941
[5]   Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their antiinflammatory properties [J].
Bartosh, Thomas J. ;
Ylostalo, Joni H. ;
Mohammadipoor, Arezoo ;
Bazhanov, Nikolay ;
Coble, Katie ;
Claypool, Kent ;
Lee, Ryang Hwa ;
Choi, Hosoon ;
Prockop, Darwin J. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (31) :13724-13729
[6]   Tracking stem cells using magnetic nanoparticles [J].
Berman, Stacey M. Cromer ;
Walczak, Piotr ;
Bulte, Jeff W. M. .
WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, 2011, 3 (04) :343-355
[7]   Nanoparticles for cell labeling [J].
Bhirde, Ashwinkumar ;
Xie, Jin ;
Swierczewska, Maggie ;
Chen, Xiaoyuan .
NANOSCALE, 2011, 3 (01) :142-153
[8]   Chondrogenic differentiation of mesenchymal stem cells is inhibited after magnetic labeling with ferumoxides [J].
Bulte, JWM ;
Kraitchman, DL ;
Mackay, AM ;
Pittenger, MF .
BLOOD, 2004, 104 (10) :3410-3412
[9]   Biomimetics of the extracellular matrix: an integrated three-dimensional fiber-hydrogel composite for cartilage tissue engineering [J].
Coburn, Jeannine ;
Gibson, Matt ;
Bandalini, Pierre Alain ;
Laird, Christopher ;
Mao, Hai-Quan ;
Moroni, Lorenzo ;
Seliktar, Dror ;
Elisseeff, Jennifer .
SMART STRUCTURES AND SYSTEMS, 2011, 7 (03) :213-222
[10]   Conserved Fate and Function of Ferumoxides-Labeled Neural Precursor Cells In Vitro and In Vivo [J].
Cohen, Mikhal E. ;
Muja, Naser ;
Fainstein, Nina ;
Bulte, Jeff W. M. ;
Ben-Hur, Tamir .
JOURNAL OF NEUROSCIENCE RESEARCH, 2010, 88 (05) :936-944