Review article: BK virus in systemic lupus erythematosus

被引：15

作者：

Gupta, Nirupama ^{[1
]}

Lawrence, Robert M. ^{[2
]}

Cuong Nguyen ^{[3
]}

Modica, Renee F. ^{[2
]}

机构：

[1] Univ Florida, Coll Med, Dept Pediat, Div Nephrol, Gainesville, FL 32610 USA

[2] Univ Florida, Coll Med, Dept Pediat, Div Immunol Rheumatol & Infect Dis, Gainesville, FL 32610 USA

[3] Univ Florida, Coll Vet Med, Dept Infect Dis & Pathol, Gainesville, FL 32610 USA

来源：

PEDIATRIC RHEUMATOLOGY | 2015年 / 13卷

关键词：

BK virus; SLE; Immunosuppression; HEART-TRANSPLANT RECIPIENT; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; CHRONIC LYMPHOCYTIC-LEUKEMIA; RENAL-ALLOGRAFT RECIPIENTS; POLYOMAVIRUS-NEPHROPATHY; NATIVE KIDNEYS; INTRAVENOUS IMMUNOGLOBULIN; INFECTIOUS COMPLICATIONS; PEDIATRIC-PATIENTS; T-ANTIGEN;

D O I：

10.1186/s12969-015-0033-9

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

BK virus (BKV) is a human polyomavirus with a seroprevalence of 60-80 % in the general population. In renal transplant patients, it is known to cause renal failure, ureteric stenosis and hemorrhagic cystitis. In bone marrow transplant patients, it is evident that BKV can also cause hemorrhagic cystitis along with BK virus nephropathy (BKVN) in the native kidneys, with subsequent renal failure. However, little is known about BVKN in non-transplanted immune-compromised patients, such as systemic lupus erythematosus (SLE) who may have underlying nephritis and have a compromised immune system due to therapy and/or systemic illness. Thus, this article will focus on the clinical aspects of BKV and its association in patients with SLE.

引用

页数：11

共 77 条

[1] Native BK viral nephropathy in a pediatric heart transplant recipient [J].

Ali, Farah N. ;

Meehan, Shane M. ;

Pahl, Elfriede ;

Cohn, Richard A. .

PEDIATRIC TRANSPLANTATION, 2010, 14 (04) :E38-E41

[2] LONG-TERM FOLLOW-UP OF PATIENTS WITH LUPUS NEPHRITIS - A STUDY BASED ON THE CLASSIFICATION OF THE WORLD-HEALTH-ORGANIZATION [J].

APPEL, GB ;

COHEN, DJ ;

PIRANI, CL ;

MELTZER, JI ;

ESTES, D .

AMERICAN JOURNAL OF MEDICINE, 1987, 83 (05) :877-885

[3]

ARTHUR RR, 1989, PROG MED VIROL, V36, P42

[4] Infections in the lupus patient: perspectives on prevention [J].

Barber, Claire ;

Gold, Wayne L. ;

Fortin, Paul R. .

CURRENT OPINION IN RHEUMATOLOGY, 2011, 23 (04) :358-365

[5]

Beimler J, 2007, NEPHROL DIAL TRANSPL, V22

[6] VP1 DNA sequences of JC and BK viruses detected in urine of systemic lupus erythematosus patients reveal no differences from strains expressed in normal individuals [J].

Bendiksen, S ;

Rekvig, OP ;

Van Ghelue, M ;

Moens, U .

JOURNAL OF GENERAL VIROLOGY, 2000, 81 :2625-2633

[7] Progressive Multifocal Leukoencephalopathy and Newer Biological Agents [J].

Berger, Joseph R. .

DRUG SAFETY, 2010, 33 (11) :969-983

[8] Human polyoma viruses and disease with emphasis on clinical BK and JC [J].

Boothpur, Raghavender ;

Brennan, Daniel C. .

JOURNAL OF CLINICAL VIROLOGY, 2010, 47 (04) :306-312

[9] Incidence of BK with tacrolimus versus cyclosporine and impact of preemptive immunosuppression reduction [J].

Brennan, DC ;

Agha, I ;

Bohl, DL ;

Schnitzler, MA ;

Hardinger, HL ;

Lockwood, M ;

Torrence, S ;

Schuessler, R ;

Roby, T ;

Gaudreault-Keener, M ;

Storch, GA .

AMERICAN JOURNAL OF TRANSPLANTATION, 2005, 5 (03) :582-594

[10] Progressive multifocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the Research on Adverse Drug Events and Reports project [J].

Carson, Kenneth R. ;

Evens, Andrew M. ;

Richey, Elizabeth A. ;

Habermann, Thomas M. ;

Focosi, Daniele ;

Seymour, John F. ;

Laubach, Jacob ;

Bawn, Susie D. ;

Gordon, Leo I. ;

Winter, Jane N. ;

Furman, Richard R. ;

Vose, Julie M. ;

Zelenetz, Andrew D. ;

Mamtani, Ronac ;

Raisch, Dennis W. ;

Dorshimer, Gary W. ;

Rosen, Steven T. ;

Muro, Kenji ;

Gottardi-Littell, Numa R. ;

Talley, Robert L. ;

Sartor, Oliver ;

Green, David ;

Major, Eugene O. ;

Bennett, Charles L. .

BLOOD, 2009, 113 (20) :4834-4840

← 1 2 3 4 5 6 7 8 →