High-Cervical Spinal Cord Stimulation for Medically Intractable Chronic Migraine

被引:26
作者
De Agostino, Rinaldo [1 ,2 ]
Federspiel, Barbara [1 ,2 ]
Cesnulis, Evaldas [3 ]
Sandor, Peter S. [4 ]
机构
[1] SeeSpital, Dept Internal Med, Horgen, Switzerland
[2] SeeSpital, Pain Clin, Horgen, Switzerland
[3] Hirslanden Hosp, Dept Neurosurg, Zurich, Switzerland
[4] Kantonsspital Baden, ANNR RehaClin, CH-5404 Baden, Switzerland
来源
NEUROMODULATION | 2015年 / 18卷 / 04期
关键词
Chronic migraine; epidural spinal cord stimulation; headache; high-cervical spinal cord stimulation; neurostimulation; OCCIPITAL NERVE-STIMULATION; GAMMA-AMINOBUTYRIC-ACID; CHRONIC PAIN; DORSAL-HORN; MEDICATION-OVERUSE; CLUSTER HEADACHE; NEUROPATHIC PAIN; ANGINA-PECTORIS; RAT MODEL; NEUROSTIMULATION;
D O I
10.1111/ner.12236
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
ObjectivesHigh-cervical spinal cord stimulation (SCS) is a promising neurostimulation method for the control of chronic pain, including chronic cluster headache. The effects of high-cervical SCS in patients with intractable chronic migraine pain are unknown. Materials and MethodsThis study is a retrospective survey of a cohort of 17 consecutive patients with medically intractable chronic migraine pain implanted with a high-cervical SCS device between 2007 and 2011. ResultsAfter a median of 15 months (range 2-48) since implantation, mean pain intensity was significantly reduced by 60% (p < 0.0001), with 71% of the patients experiencing a decrease of 50% or more. The median number of days with migraine decreased from 28 (range 12-28) to 9.0 (range 0-28) days (p = 0.0313). Quality of life was significantly improved (p = 0.0006), and the proportion of patients not requiring pain medication increased from 0.0% to 37.5% (p = 0.0313). Use of pharmacological and nonpharmacological treatments of migraine was decreased. Working capacity was not significantly improved. Complications were infrequent: three infections (13.0% of all implanted) and three lead dislocations (17.6% of all included). ConclusionIn patients with intractable chronic migraine treated with high-cervical SCS, pain and quality of life significantly improved, warranting further research.
引用
收藏
页码:289 / 296
页数:8
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