Could more effective use of kidneys recovered from older deceased donors result in more kidney transplants for older patients?

被引:56
作者
Cecka, JM
Cohen, B
Rosendale, J
Smith, M
机构
[1] Univ Calif Los Angeles, Immunogenet Ctr, Dept Pathol, Los Angeles, CA 90024 USA
[2] Eurotransplant Fdn, Leiden, Netherlands
[3] United Network Oran Sharing, Richmond, VA USA
关键词
kidney; discard; older donor; transplant;
D O I
10.1097/01.tp.0000216284.81604.d4
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In the face of a severe shortage of kidneys from deceased organ donors that limits access to transplantation for many patients, about one of every seven kidneys (more than 1,500 each year) recovered from deceased donors in the United States are not transplanted. Eurotransplant, which coordinates organ distribution for six countries and a population of about 118 million, discards only one of every 20 kidneys procured for transplantation. We compared kidney procurement, transplants, and discards between January 2000 and June 2003 in the United States and in the Eurotransplant region using the Organ procurement and Transplantation Network/United Network for Organ Sharing and Eurotransplant databases to examine differences that might account for this wide disparity.
引用
收藏
页码:966 / 970
页数:5
相关论文
共 17 条
[1]   Expanded criteria donor kidney allocation: Marked decrease in cold ischemia and delayed graft function at a single center [J].
Carter, JT ;
Chan, S ;
Roberts, JP ;
Feng, S .
AMERICAN JOURNAL OF TRANSPLANTATION, 2005, 5 (11) :2745-2753
[2]   Expanding the donor pool to increase renal transplantation [J].
Cohen, B ;
Smits, JM ;
Haase, B ;
Persijn, G ;
Vanrenterghem, Y ;
Frei, U .
NEPHROLOGY DIALYSIS TRANSPLANTATION, 2005, 20 (01) :34-41
[3]   The new eurotransplant kidney allocation system - Report one year after implementation [J].
De Meester, J ;
Persijn, GG ;
Wujciak, T ;
Opelz, G ;
Vanrenterghem, Y .
TRANSPLANTATION, 1998, 66 (09) :1154-1159
[4]   Reasons for non-use of recovered kidneys: The effect of donor glomerulosclerosis and creatinine clearance on graft survival [J].
Edwards, EB ;
Posner, MP ;
Maluf, DG ;
Kauffman, HM .
TRANSPLANTATION, 2004, 77 (09) :1411-1415
[5]   GLOMERULOSCLEROSIS AS A DETERMINANT OF POSTTRANSPLANT FUNCTION OF OLDER DONOR RENAL-ALLOGRAFTS [J].
GABER, LW ;
MOORE, LW ;
ALLOWAY, RR ;
AMIRI, MH ;
VERA, SR ;
GABER, AO .
TRANSPLANTATION, 1995, 60 (04) :334-339
[6]   Determinants of cardiovascular mortality after renal transplantation: A role for cytomegalovirus? [J].
Kalil, RSN ;
Hudson, SL ;
Gaston, RS .
AMERICAN JOURNAL OF TRANSPLANTATION, 2003, 3 (01) :79-81
[7]  
MCBRIDE MA, 2004, CLIN TRANSPLANTS 200, P53
[8]   Kidneys from deceased donors: Maximizing the value of a scarce resource [J].
Meier-Kriesche, HU ;
Schold, JD ;
Gaston, RS ;
Wadstrom, J ;
Kaplan, B .
AMERICAN JOURNAL OF TRANSPLANTATION, 2005, 5 (07) :1725-1730
[9]   Expanded criteria donors for kidney transplantation [J].
Metzger, RA ;
Delmonico, FL ;
Feng, S ;
Port, FK ;
Wynne, JJ ;
Merion, RM .
AMERICAN JOURNAL OF TRANSPLANTATION, 2003, 3 :114-125
[10]  
Miranda B, 2003, Ann Transplant, V8, P9