Stable end-to-end assembly of gold nanorods directed by cyclic disulfide-modified DNA

被引：5
|
作者：
Zhang, Zhiliang [1 ]
Wen, Yongqiang [2 ]
Zhao, Dan [2 ]
Zhang, Xueji [2 ]
机构：
[1] Shandong Polytech Univ, Res Ctr Anal & Test, Jinan 250353, Peoples R China
[2] Univ Sci & Technol Beijing, Res Ctr Bioengn & Sensing Technol, Beijing 100083, Peoples R China
来源：
APPLIED PHYSICS LETTERS | 2012年 / 101卷 / 21期
关键词：
NANOPARTICLES; DISCRETE;
D O I：
10.1063/1.4767392
中图分类号：
O59 [应用物理学];
学科分类号：
摘要：
In this work, a highly stable end-to-end assembly of gold nanorods based on the oligonucleotide hybridization has been achieved. In this system, a special triple cyclic disulfide-modified DNA molecule was elaborately designed and immobilized on the end faces of gold nanorods. The polyvalent linkages between gold nanorods and cyclic disulfide groups-modified DNA tremendously increased the stability of the end-to-end assembly. The assembly strategy showed good controllability, and could be used for the assembly of more complex functional nanodevices and sensors in biological detection fields. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.4767392]
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页数：4
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