Surgical mitral plasticity for chronic ischemic mitral regurgitation

被引:13
作者
Calafiore, Antonio M. [1 ]
Totaro, Antonio [1 ]
De Amicis, Vincenzo [2 ]
Pelini, Piero [3 ]
Pinna, Giovanni [2 ]
Testa, Nicola [1 ]
Alfonso, Juan J. [4 ]
Mazzei, Valerio [1 ]
Sacra, Cosimo [1 ]
Gaudino, Mario [5 ]
Di Mauro, Michele [3 ]
机构
[1] Gemelli Molise, Dept Cardiovasc Dis, Campobasso, Italy
[2] Univ Naples Federico II, Div Cardiac Surg, Naples, Italy
[3] DAnnunzio Univ, Div Cardiac Surg, Chieti, Italy
[4] Prince Sultan Cardiac Ctr, Dept Res, Riyadh, Saudi Arabia
[5] Weill Cornell Med, Dept Cardiothorac Surg, New York, NY USA
关键词
mitral regurgitation; mitral valve; valve repair; replacement; ANTERIOR LEAFLET AUGMENTATION; EUROPEAN-ASSOCIATION; ADAPTATION; ECHOCARDIOGRAPHY; ANNULOPLASTY; RECOMMENDATIONS; QUANTIFICATION; VALIDATION; COAPTATION; REPAIR;
D O I
10.1111/jocs.14487
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background and Aim of the Study The outcome of mitral valve (MV) repair for chronic ischemic mitral regurgitation (IMR) is suboptimal, due to the high recurrence rate of moderate or severe mitral regurgitation (MR) during follow-up. The MV adapts to new MR increasing its area to cover the enlarged annular area (mitral plasticity). As this process is often incomplete, we aimed to evaluate if augmenting the anterior leaflet (AL) and cutting the second-order chords (CC) together with restrictive mitral annuloplasty, a strategy we call "surgical mitral plasticity," could improve the midterm results of MV repair for IMR. Materials and Methods From November 2017 to October 2019, 22 patients with chronic IMR underwent surgical mitral plasticity. Mean age was 73 +/- 7 years and six were female. Mean ejection fraction was 32% +/- 11%, IMR grade was moderate in 10 and severe in 12. Mean clinical and echocardiographic follow-up was 12 +/- 6 months. Results There was no early death, and one patient died 6 months after surgery. Ejection fraction improved from 32% +/- 15% to 40% +/- 6% (P = .031). IMR was absent or mild in all patients, and none showed recurrent moderate or more IMR. Tenting area decreased significantly from 2.5 +/- 0.5 to 0.5 +/- 0.3 cm(2) and coaptation length increased from 1.9 +/- 0.7 to 7.8 +/- 1.6 mm. All patients were in New York Heart Association class I or II. Conclusions Mitral plasticity, if uncomplete, is ineffective in preventing IMR to become significant. Surgical mitral plasticity, by completing incomplete process of MV adaptation, has a strong rationale, which however needs to be validated with longer follow-up.
引用
收藏
页码:772 / 778
页数:7
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