Uremic pruritus

被引：23

作者：

Kfoury, Lara W. ^{[1
]}

Jurdi, Makram A. ^{[2
]}

机构：

[1] Brown Univ, Alpert Med Sch, Dept Internal Med, Div Renal Dis & Hypertens, Providence, RI 02912 USA

[2] E Tennessee State Univ, Coll Med, Dept Internal Med, Johnson City, TN 37614 USA

来源：

JOURNAL OF NEPHROLOGY | 2012年 / 25卷 / 05期

关键词：

End-stage renal disease; Pruritus; Uremic; HEMODIALYSIS-RELATED PRURITUS; DOUBLE-BLIND; ULTRAVIOLET PHOTOTHERAPY; ERYTHROPOIETIN THERAPY; GENERALIZED PRURITUS; TACROLIMUS OINTMENT; DIALYSIS PATIENTS; PLASMA HISTAMINE; GABAPENTIN; NALTREXONE;

D O I：

10.5301/jn.5000039

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Uremic pruritus remains one of the most frustrating and potentially disabling symptoms in patients with end-stage renal disease. It affects up to 90% of patients on dialysis. Several hypotheses have been postulated for the possible underlying etiology, but none is conclusive. Aside from kidney transplantation, which is the only definitive treatment, therapeutic approaches have largely been empirical, and no firm evidence-based treatments are available. The main goal of therapy remains to minimize the severity of pruritus and improve the quality of life especially among those who are not transplantation candidates or are waiting for surgery.

引用

页码：644 / 652

页数：9

共 75 条

[1] Treatment of uremic pruritus with narrowband ultraviolet B phototherapy:: An open pilot study [J].

Ada, S ;

Seçkin, D ;

Budakoglu, I ;

Özdemir, FN .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2005, 53 (01) :149-151

[2]

ANDERSEN LW, 1984, CLIN NEPHROL, V21, P355

[3] Ondansetron therapy for uremic pruritus in hemodialysis patients [J].

Ashmore, SD ;

Jones, CH ;

Newstead, CG ;

Daly, MJ ;

Chrystyn, H .

AMERICAN JOURNAL OF KIDNEY DISEASES, 2000, 35 (05) :827-831

[4] Randomized, Double-blind Study with Glycerol and Paraffin in Uremic Xerosis [J].

Balaskas, Elias ;

Szepietowski, Jacek C. ;

Bessis, Didier ;

Ioannides, Dimitrios ;

Ponticelli, Claudio ;

Ghienne, Corinne ;

Taberly, Alain ;

Dupuy, Patrick .

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2011, 6 (04) :748-752

[5]

BALASKAS EV, 1995, PERITON DIALYSIS INT, V15, P177

[6] UREMIC PRURITUS - SKIN DIVALENT ION CONTENT AND RESPONSE TO ULTRAVIOLET PHOTOTHERAPY [J].

BLACHLEY, JD ;

BLANKENSHIP, DM ;

MENTER, A ;

PARKER, TF ;

KNOCHEL, JP .

AMERICAN JOURNAL OF KIDNEY DISEASES, 1985, 5 (05) :237-241

[7] DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY OF NICERGOLINE IN THE TREATMENT OF PRURITUS IN PATIENTS RECEIVING MAINTENANCE HEMODIALYSIS [J].

BOUSQUET, J ;

RIVORY, JP ;

MAHEUT, M ;

MICHEL, FB ;

MION, C .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1989, 83 (04) :825-828

[8] MAGNESIUM FREE DIALYSIS FOR UREMIC PRURITUS [J].

CARMICHAEL, AJ ;

DICKINSON, F ;

MCHUGH, MI ;

MARTIN, AM ;

FARROW, M .

BRITISH MEDICAL JOURNAL, 1988, 297 (6663) :1584-1585

[9] Therapeutic effect of topical gamma-linolenic acid on refractory uremic pruritus [J].

Chen, Yung-Chih ;

Chiu, Wan-Ting ;

Wu, Mai-Szu .

AMERICAN JOURNAL OF KIDNEY DISEASES, 2006, 48 (01) :69-76

[10] Uremic pruritus: Roles of parathyroid hormone and substance P [J].

Cho, YL ;

Liu, HN ;

Huang, TP ;

Tarng, DC .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1997, 36 (04) :538-543

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