Epithelioid malignant peripheral nerve sheath tumor arising in schwannoma

被引：9

作者：

Heatley, Nicholas ^{[1
]}

Kokohaare, Eva Kolson ^{[1
]}

Strauss, Dirk C. ^{[1
]}

Hallin, Magnus ^{[1
]}

Jones, Robin L. ^{[1
,2
]}

Fisher, Cyril ^{[2
,3
]}

Thway, Khin ^{[1
,2
]}

机构：

[1] Royal Marsden Hosp, Sarcoma Unit, London, England

[2] Inst Canc Res, London, England

[3] Univ Birmingham, Royal Orthopaed Hosp NHS Fdn Trust, Robert Aitken Inst Clin Res, Dept Musculoskeletal Pathol, Birmingham, W Midlands, England

来源：

RARE TUMORS | 2020年 / 12卷

关键词：

Epithelioid malignant peripheral nerve sheath tumor; extremity; sarcoma; schwannoma; SMARCB1; INI1gene; thigh; DIAGNOSTIC FEATURES; SOFT-TISSUE; SUPPRESSOR; MARKER; PRC2;

D O I：

10.1177/2036361320950862

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Epithelioid malignant peripheral nerve sheath tumor (EMPNST, malignant epithelioid schwannoma) is a rare variant of malignant peripheral nerve sheath tumor that has morphologic and immunophenotypic overlap with a variety of epithelioid neoplasms. Because of its rarity it may be potentially underrecognized. We describe a case arising in the subcutis of the thigh in a 25 year-old female, and discuss the pathologic features and differential diagnosis.

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