Non-Typhoidal Salmonella Gastroenteritis at a Diarrheal Hospital in Dhaka, Bangladesh, 1996-2011

被引:19
作者
Leung, Daniel T. [1 ]
Das, Sumon K. [2 ]
Malek, M. A. [2 ]
Ahmed, Dilruba [3 ]
Khanam, Farhana [1 ]
Qadri, Firdausi [1 ]
Faruque, A. S. G. [2 ]
Ryan, Edward T. [4 ]
机构
[1] Int Ctr Diarrhoeal Dis Res, Ctr Vaccine Sci, Bangladesh ICDDR B, Dhaka 1000, Bangladesh
[2] Int Ctr Diarrhoeal Dis Res, Ctr Nutr & Food Secur, Bangladesh ICDDR B, Dhaka 1000, Bangladesh
[3] Int Ctr Diarrhoeal Dis Res, Clin Microbiol Lab, Bangladesh ICDDR B, Dhaka 1000, Bangladesh
[4] Massachusetts Gen Hosp, Div Infect Dis, Boston, MA 02114 USA
基金
美国国家卫生研究院;
关键词
ANTIMICROBIAL RESISTANCE; CHILDHOOD DIARRHEA; ASIAN COUNTRIES; INFECTIONS; CHILDREN; DISEASE; SURVEILLANCE; BACTEREMIA; AFRICA; ENTEROPATHOGENS;
D O I
10.4269/ajtmh.12-0672
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Data on non-typhoidal Salmonella (NTS) infection in South Asia are limited. We used data gathered prospectively from 1996 to 2011 as part of a hospital surveillance system in Dhaka, Bangladesh, to identify diarrheal patients with NTS isolated from stool. NTS was isolated in 1.3% (468 of 37,439) of diarrheal patients; 47% of total cases of NTS were in children <5 years of age, although older adults (>= 60 years) had the highest isolation rates. NTS isolation peaked in the monsoon months of July and August. Over the study period, rates of multidrug resistance decreased, whereas rates of decreased susceptibility to ciprofloxacin increased. Compared with control patients, NTS patients were older and wealthier; however, no differences in type of housing or exposure to animals were found. NTS patients had increased inflammatory cells in stool and required more fluid resuscitation.
引用
收藏
页码:661 / 669
页数:9
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