Left atrial appendage closure devices. Their role in 2013

被引：0

作者：

Mangner, N. ^{[1
]}

Sandri, M. ^{[1
]}

Lurz, P. ^{[1
]}

Daehnert, I. ^{[2
]}

Schuler, G. ^{[1
]}

Moebius-Winkler, S. ^{[3
]}

机构：

[1] Univ Leipzig, Ctr Heart, Dept Internal Med Cardiol, D-04109 Leipzig, Germany

[2] Univ Leipzig, Ctr Heart, Dept Pediat Cardiol, D-04109 Leipzig, Germany

[3] Asklepios Clin Weissenfels, Dept Cardiol, D-06667 Weissenfels, Germany

来源：

MINERVA CARDIOANGIOLOGICA | 2013年 / 61卷 / 02期

关键词：

Stroke; Warfarin; Atrial fibrillation; RISK STRATIFICATION SCHEMES; SPONTANEOUS ECHO CONTRAST; AMPLATZER CARDIAC PLUG; STROKE PREVENTION; TRANSCATHETER OCCLUSION; CLINICAL-IMPLICATIONS; PERCUTANEOUS CLOSURE; THROMBOEMBOLIC RISK; EMBOLIC PROTECTION; PREDICTING STROKE;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Stroke prevention is the major goal in treating patients with atrial fibrillation. Warfarin therapy, if used appropriately, is highly effective in preventing thromboembolic events, but is simultaneously burdened by a narrow therapeutic window, multiple food and drug interactions, and a substantial bleeding risk. New pharmacological agents show only a modest reduction of bleeding complications compared to warfarin. Percutaneous device left atrial appendage (LAA) closure has now been technologically advanced as an additional and potential alternative to pharmacotherapy in patients with AF. Promising randomized data are obtainable with the WATCHMAN (R) device, while several other devices are in various stages of clinical and preclinical development. In this article we review the current knowledge and status of this technique.

引用

页码：125 / 134

页数：10

共 76 条

[31] Apixaban versus Warfarin in Patients with Atrial Fibrillation [J].

Granger, Christopher B. ;

Alexander, John H. ;

McMurray, John J. V. ;

Lopes, Renato D. ;

Hylek, Elaine M. ;

Hanna, Michael ;

Al-Khalidi, Hussein R. ;

Ansell, Jack ;

Atar, Dan ;

Avezum, Alvaro ;

Cecilia Bahit, M. ;

Diaz, Rafael ;

Easton, J. Donald ;

Ezekowitz, Justin A. ;

Flaker, Greg ;

Garcia, David ;

Geraldes, Margarida ;

Gersh, Bernard J. ;

Golitsyn, Sergey ;

Goto, Shinya ;

Hermosillo, Antonio G. ;

Hohnloser, Stefan H. ;

Horowitz, John ;

Mohan, Puneet ;

Jansky, Petr ;

Lewis, Basil S. ;

Luis Lopez-Sendon, Jose ;

Pais, Prem ;

Parkhomenko, Alexander ;

Verheugt, Freek W. A. ;

Zhu, Jun ;

Wallentin, Lars .

NEW ENGLAND JOURNAL OF MEDICINE, 2011, 365 (11) :981-992

[32] Left Atrial Appendage Closure with the Amplatzer Cardiac Plug in Patients with Atrial Fibrillation [J].

Guerios, Enio Eduardo ;

Schmid, Michael ;

Gloekler, Steffen ;

Khattab, Ahmed A. ;

Wenaweser, Peter M. ;

Windecker, Stephan ;

Meier, Bernhard .

ARQUIVOS BRASILEIROS DE CARDIOLOGIA, 2012, 98 (06) :528-536

[33] Pharmacologic and Nonpharmacologic Therapies for Stroke Prevention in Nonvalvular Atrial Fibrillation [J].

Han, Jiangli ;

Cheng, Jie ;

Mathuria, Nilesh .

PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 2012, 35 (07) :887-896

[34] Left Atrial Appendage Occlusion Study (LAAOS): Results of a randomized controlled pilot study of left atrial appendage occlusion during coronary bypass surgery in patients at risk for stroke [J].

Healey, JS ;

Crystal, E ;

Lamy, A ;

Teoh, K ;

Semelhago, L ;

Hohnloser, SH ;

Cybulsky, I ;

Abouzahr, L ;

Sawchuck, C ;

Carroll, S ;

Morillo, C ;

Kleine, P ;

Chu, V ;

Lonn, E ;

Connolly, SJ .

AMERICAN HEART JOURNAL, 2005, 150 (02) :288-293

[35] Percutaneous closure of the left atrial appendage versus warfarin therapy for prevention of stroke in patients with atrial fibrillation: a randomised non-inferiority trial [J].

Holmes, David R. ;

Reddy, Vivek Y. ;

Turi, Zoltan G. ;

Doshi, Shephal K. ;

Sievert, Horst ;

Buchbinder, Maurice ;

Mullin, Christopher M. ;

Sick, Peter .

LANCET, 2009, 374 (9689) :534-542

[36] CLINICAL IMPLICATIONS AND FACTORS RELATED TO LEFT ATRIAL SPONTANEOUS ECHO CONTRAST IN CHRONIC NONVALVULAR ATRIAL-FIBRILLATION [J].

HWANG, JJ ;

KO, FN ;

LI, YH ;

MA, HM ;

WU, GJ ;

CHANG, H ;

WANG, SM ;

SCHIE, JT ;

TSENG, YZ ;

KUAN, P ;

TENG, CM ;

LIEN, WP .

CARDIOLOGY, 1994, 85 (02) :69-75

[37] Surgical left atrial appendage ligation is frequently incomplete: a transesophageal echocardiographic study [J].

Katz, ES ;

Tsiamtsiouris, T ;

Applebaum, RM ;

Schwartzbard, A ;

Tunick, PA ;

Kronzon, I .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2000, 36 (02) :468-471

[38] Outcome parameters for trials in atrial fibrillation: executive summary [J].

Kirchhof, Paulus ;

Auricchio, Angelo ;

Bax, Jeroen ;

Crijns, Harry ;

Camm, John ;

Diener, Hans-Christoph ;

Goette, Andreas ;

Hindricks, Gerd ;

Hohnloser, Stefan ;

Kappenberger, Lukas ;

Kuck, Karl-Heinz ;

Lip, Gregory Y. H. ;

Olsson, Bertil ;

Meinertz, Thomas ;

Priori, Silvia ;

Ravens, Ursula ;

Steinbeck, Gerhard ;

Svernhage, Elisabeth ;

Tijssen, Jan ;

Vincent, Alphons ;

Breithardt, Guenter .

EUROPEAN HEART JOURNAL, 2007, 28 (22) :2803-2817

[39] CLINICAL IMPLICATIONS OF LEFT ATRIAL APPENDAGE FLOW PATTERNS IN NONRHEUMATIC ATRIAL-FIBRILLATION [J].

LI, YH ;

LAI, LP ;

SHYU, KG ;

HWANG, JJ ;

KUAN, PL ;

LIEN, WP .

CHEST, 1994, 105 (03) :748-752

[40] Comparative Validation of a Novel Risk Score for Predicting Bleeding Risk in Anticoagulated Patients With Atrial Fibrillation The HAS-BLED (Hypertension, Abnormal Renal/Liver Function, Stroke, Bleeding History or Predisposition, Labile INR, Elderly, Drugs/Alcohol Concomitantly) Score [J].

Lip, Gregory Y. H. ;

Frison, Lars ;

Halperin, Jonathan L. ;

Lane, Deirdre A. .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2011, 57 (02) :173-180

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