Left atrial appendage closure devices. Their role in 2013

被引：0

作者：

Mangner, N. ^{[1
]}

Sandri, M. ^{[1
]}

Lurz, P. ^{[1
]}

Daehnert, I. ^{[2
]}

Schuler, G. ^{[1
]}

Moebius-Winkler, S. ^{[3
]}

机构：

[1] Univ Leipzig, Ctr Heart, Dept Internal Med Cardiol, D-04109 Leipzig, Germany

[2] Univ Leipzig, Ctr Heart, Dept Pediat Cardiol, D-04109 Leipzig, Germany

[3] Asklepios Clin Weissenfels, Dept Cardiol, D-06667 Weissenfels, Germany

来源：

MINERVA CARDIOANGIOLOGICA | 2013年 / 61卷 / 02期

关键词：

Stroke; Warfarin; Atrial fibrillation; RISK STRATIFICATION SCHEMES; SPONTANEOUS ECHO CONTRAST; AMPLATZER CARDIAC PLUG; STROKE PREVENTION; TRANSCATHETER OCCLUSION; CLINICAL-IMPLICATIONS; PERCUTANEOUS CLOSURE; THROMBOEMBOLIC RISK; EMBOLIC PROTECTION; PREDICTING STROKE;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Stroke prevention is the major goal in treating patients with atrial fibrillation. Warfarin therapy, if used appropriately, is highly effective in preventing thromboembolic events, but is simultaneously burdened by a narrow therapeutic window, multiple food and drug interactions, and a substantial bleeding risk. New pharmacological agents show only a modest reduction of bleeding complications compared to warfarin. Percutaneous device left atrial appendage (LAA) closure has now been technologically advanced as an additional and potential alternative to pharmacotherapy in patients with AF. Promising randomized data are obtainable with the WATCHMAN (R) device, while several other devices are in various stages of clinical and preclinical development. In this article we review the current knowledge and status of this technique.

引用

页码：125 / 134

页数：10

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