Antibacterial and cytotoxic activities of a green synthesized silver nanoparticles using corn silk aqueous extract

被引：25

作者：

Li, Ruilin ^{[1
]}

Pan, Yuxiang ^{[1
]}

Li, Nannan ^{[1
]}

Wang, Qirou ^{[1
]}

Chen, Yue ^{[1
]}

Phisalaphong, Muenduen ^{[2
]}

Chen, Haixia ^{[1
]}

机构：

[1] Tianjin Univ, Sch Pharmaceut Sci & Technol, Tianjin Key Lab Modern Drug Delivery & High Effic, Tianjin 300072, Peoples R China

[2] Chulalongkorn Univ, Dept Chem Engn, Phayathai Rd, Bangkok 10330, Thailand

来源：

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS | 2020年 / 598卷 / 598期

基金：

中国国家自然科学基金;

关键词：

Corn silk; Green synthesis; AgNPs; Antibacterial; Cytotoxicity; HIGH-FAT DIET; ECOFRIENDLY SYNTHESIS; LEAF EXTRACT; AG; ANTIOXIDANT; DRUG; BIOSYNTHESIS; GOLD; AU;

D O I：

10.1016/j.colsurfa.2020.124827

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The present work described an ecofriendly method for the synthesis of silver nanoparticles (AgNPs) by aqueous extract of corn silk. Bio-reduction of silver was complete when the mixture (AgNO3 + extract) changed its color from light yellow to reddish-brown. Corn silk aqueous extracts were screened for Total Phenolic contents (TPC), Total Flavonoid contents (TFC) and total reducing sugar content with the values of 106.4 +/- 9.6 mg/g, 42.8 +/- 3.7 mg/g, 96.0 +/- 4.4 mg/g, respectively. AgNPs were characterized by UV-vis spectroscopy, dynamic light scattering (DLS), fourier transform infrared spectroscopy (FT-IR), scanning electron microscope (SEM), energy dispersive X-ray spectroscopy (EDX) and X-ray diffraction (XRD) analysis. Different pH value, temperature and AgNO3 concentration were optimized by UV-vis spectroscopy and the mean particle size was in the range of 10-30 nm. FT-IR spectroscopy scrutinized the involvement of various functional groups during nanoparticle synthesis. SEM analysis confirmed the morphology of the synthesized nanoparticles. XRD also confirmed the formation of small spherical silver nanoparticles. In addition, green synthesized AgNPs showed efficient antimicrobial activities against both Gram-positive and Gram-negative bacteria. Further, dose response cytotoxicity on HepG2 cell was found by MTT assay with the inhibitory concentrations (IC50) value of 53 mu g/mL. The study suggested that this green and simple procedure for preparing AgNPs had an underestimated potential in biomedical, antimicrobial and nanotechnological applications.

引用

页数：8

共 38 条

[1] Green synthesis of silver nanoparticles using turmeric extracts and investigation of their antibacterial activities [J].