Development of a DNA sensor using a molecular logic gate

被引:15
|
作者
Bhattacharjee, D. [1 ]
Dey, Dibyendu [1 ]
Chakraborty, S. [1 ]
Hussain, Syed Arshad [1 ]
Sinha, S. [2 ]
机构
[1] Tripura Univ, Dept Phys, Thin Film & Nanosci Lab, Suryamaninagar 799022, Tripura, India
[2] Tripura Univ, Dept Bot, Suryamaninagar 799022, Tripura, India
关键词
FRET; DNA; Molecular logic gate; Sensor; FLUORESCENCE SWITCH; ENERGY-TRANSFER; SYSTEM;
D O I
10.1007/s10867-012-9295-3
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
This communication reports the increase in fluorescence resonance energy transfer (FRET) efficiency between two laser dyes in the presence of deoxyribonucleic acid (DNA). Two types of molecular logic gates have been designed where DNA acts as input signal and fluorescence intensity of different bands are taken as output signal. Use of these logic gates as a DNA sensor has been demonstrated.
引用
收藏
页码:387 / 394
页数:8
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