Expert consensus document from the European Society of Cardiology on catheter-based renal denervation

被引：216

作者：

Mahfoud, Felix ^{[1
]}

Luescher, Thomas Felix ^{[2
]}

Andersson, Bert ^{[3
]}

Baumgartner, Iris ^{[4
,5
]}

Cifkova, Renata ^{[6
,7
]}

DiMario, Carlo ^{[8
]}

Doevendans, Pieter ^{[9
,10
]}

Fagard, Robert ^{[11
]}

Fajadet, Jean ^{[12
]}

Komajda, Michel ^{[13
]}

LeFevre, Thierry ^{[14
]}

Lotan, Chaim ^{[15
]}

Sievert, Horst ^{[16
]}

Volpe, Massimo ^{[17
,18
]}

Widimsky, Petr ^{[19
]}

Wijns, William ^{[20
]}

Williams, Bryan ^{[21
]}

Windecker, Stephan ^{[5
,22
]}

Witkowski, Adam ^{[23
]}

Zeller, Thomas ^{[24
]}

Boehm, Michael ^{[1
]}

机构：

[1] Univ Klinikum Saarlandes, Innere Med Klin 3, Homburg, Saar, Germany

[2] Univ Zurich Hosp, Dept Cardiol, Ctr Cardiovasc, CH-8091 Zurich, Switzerland

[3] Sahlgrens Univ Hosp, Dept Cardiol, Gothenburg, Sweden

[4] Univ Bern, Swiss Cardiovasc Ctr, Bern, Switzerland

[5] Univ Hosp Bern, CH-3010 Bern, Switzerland

[6] Charles Univ Prague, Sch Med 1, Ctr Cardiovasc Prevent, Prague, Czech Republic

[7] Thomayer Hosp, Prague, Czech Republic

[8] Royal Brompton & Harefield NHS Trust, NIHR Cardiovasc BRU, London, England

[9] UMCU Utrecht Netherlands, Dept Cardiol, Utrecht, Netherlands

[10] ICIN Utrecht, Utrecht, Netherlands

[11] Katholieke Univ Leuven, Dept Cardiovasc Dis, Louvain, Belgium

[12] Clin Pasteur, Intervent Cardiol Unit, Toulouse, France

[13] Univ Paris 06, Pitie Salpetriere Hosp, Dept Cardiol, Paris, France

[14] Hop Jacques Cartier, Inst Cardiovasc Paris Sud, Massy, France

[15] Hadassah Hebrew Univ, Med Ctr, Inst Heart, Jerusalem, Israel

[16] Sankt Katharinen, CardioVasc Ctr Frankfurt, Frankfurt, Germany

[17] Univ Roma La Sapienza, Div Cardiol, Dept Clin & Mol Med, St Andrea Hosp, I-00185 Rome, Italy

[18] IRCCS Neuromed, Pozzilli, IS, Italy

[19] Charles Univ Prague, Cardioctr, Hosp Royal Vineyards, Prague, Czech Republic

[20] Cardiovasc Ctr Aalst, Aalst, Belgium

[21] UCL, Inst Cardiovasc Sci, London, England

[22] Univ Bern, Kardiol Klin, Bern, Switzerland

[23] Inst Cardiol, Dept Intervent Cardiol & Angiol, Warsaw, Poland

[24] Univ Herzzentrum Freiburg Bad Krozingen, Klin Kardiol & Angiol 2, Bad Krozingen, Germany

来源：

EUROPEAN HEART JOURNAL | 2013年 / 34卷 / 28期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1093/eurheartj/eht154

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Current evidence from the available clinical trials strongly support the notion that catheter-based radiofrequency ablation of renal nerves reduces blood pressure and improves blood pressure control in patients with drug-treated resistant hypertension, with data now extending out to 36 months. Accordingly, renal denervation can be considered as a therapeutic option in patients with resistant hypertension, whose blood pressure cannot be controlled by a combination of lifestyle modification and pharmacological therapy according to current guidelines. The fact that renal denervation also reduces whole-bodysympathetic nerve activity suggests that this therapy may also be beneficial in other clinical states characterized by sympathetic nervous system activation-this may ultimately lead to new indications. © The Author 2013.

引用

页码：2149 / 2157

页数：9

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