High field dynamic nuclear polarization at 6.7 T: Carbon-13 polarization above 70% within 20 min

被引：110

作者：

Jannin, Sami ^{[1
]}

Bornet, Aurelien ^{[1
]}

Melzi, Roberto ^{[2
]}

Bodenhausen, Geoffrey ^{[1
,3
,4
,5
]}

机构：

[1] Ecole Polytech Fed Lausanne, Inst Sci & Ingn Chim, CH-1015 Lausanne, Switzerland

[2] Bruker Italia Srl, I-20158 Milan, Italy

[3] Ecole Normale Super, Dept Chim, F-75231 Paris 05, France

[4] Univ Paris 06, Paris, France

[5] CNRS UPMC ENS, UMR 7203, Paris, France

来源：

CHEMICAL PHYSICS LETTERS | 2012年 / 549卷

基金：

瑞士国家科学基金会;

关键词：

MAGNETIC RESONANCE SATURATION; RODENT MRI SCANNER; CROSS-POLARIZATION; PROTON POLARIZATION; NMR; TEMPERATURES; PRINCIPLES; SOLIDS;

D O I：

10.1016/j.cplett.2012.08.017

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

In most applications of dissolution-DNP, the polarization of nuclei with low gyromagnetic ratios such as C-13 is enhanced directly by irradiating the ESR transitions of radicals with narrow ESR lines such as Trityl at low temperatures T = 1.2 K in polarizing fields B-0 <= 5 T. In a field B-0 = 6.7 T at T = 1.2 K, DNP with TEMPO leads to a rapid build-up of proton polarization P(H-1) = 91% with tau(DNP)(1H) = 150 s. CP at low temperatures yields a polarization P(H-1 -> C-13) in excess of 70% within 20 min. After rapid dissolution to room temperature, this is 122000 times larger than the Boltzmann polarization at 300 K and 6.7 T. (c) 2012 Elsevier B.V. All rights reserved.

引用

页码：99 / 102

页数：4

共 20 条

[1] PRINCIPLES OF DYNAMIC NUCLEAR-POLARIZATION [J].

ABRAGAM, A ;

GOLDMAN, M .

REPORTS ON PROGRESS IN PHYSICS, 1978, 41 (03) :395-467

[2] Increase in signal-to-noise ratio of >10,000 times in liquid-state NMR [J].

Ardenkjaer-Larsen, JH ;

Fridlund, B ;

Gram, A ;

Hansson, G ;

Hansson, L ;

Lerche, MH ;

Servin, R ;

Thaning, M ;

Golman, K .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (18) :10158-10163

[3] SPIN-TEMPERATURE MODEL OF NUCLEAR DYNAMIC POLARIZATION USING FREE RADICALS [J].

BORGHINI, M .

PHYSICAL REVIEW LETTERS, 1968, 20 (09) :419-&

[4] Cross Polarization for Dissolution Dynamic Nuclear Polarization Experiments at Readily Accessible Temperatures 1.2 < T < 4.2 K [J].

Bornet, Aurelien ;

Melzi, Roberto ;

Jannin, Sami ;

Bodenhausen, Geoffrey .

APPLIED MAGNETIC RESONANCE, 2012, 43 (1-2) :107-117

[5] Principles of operation of a DNP prepolarizer coupled to a rodent MRI scanner [J].

Comment, A. ;

van den Brandt, B. ;

Uffmann, K. ;

Kurdzesau, F. ;

Jannin, S. ;

Konter, J. A. ;

Hautle, P. ;

Wenckebach, W. T. ;

Gruetter, R. ;

van der Klink, J. J. .

APPLIED MAGNETIC RESONANCE, 2008, 34 (3-4) :313-319

[6] Design and performance of a DNP prepolarizer coupled to a rodent MRI scanner [J].

Comment, A. ;

van den Brandt, B. ;

Uffmann, K. ;

Kurdzesau, F. ;

Jannin, S. ;

Konter, J. A. ;

Hautle, P. ;

Wenckebach, W. TH. ;

Gruetter, R. ;

van der Klink, J. J. .

CONCEPTS IN MAGNETIC RESONANCE PART B-MAGNETIC RESONANCE ENGINEERING, 2007, 31B (04) :255-269

[7] HIGH-FREQUENCY (140 GHZ) DYNAMIC NUCLEAR-POLARIZATION - POLARIZATION TRANSFER TO A SOLUTE IN FROZEN AQUEOUS-SOLUTION [J].

GERFEN, GJ ;

BECERRA, LR ;

HALL, DA ;

GRIFFIN, RG ;

TEMKIN, RJ ;

SINGEL, DJ .

JOURNAL OF CHEMICAL PHYSICS, 1995, 102 (24) :9494-9497

[8] PROTON POLARIZATION IN ALCOHOLS AT 50 KG, 1K [J].

HARTMANN, G ;

HUBERT, D ;

MANGO, S ;

MOREHOUS.CC ;

PLOG, K .

NUCLEAR INSTRUMENTS & METHODS, 1973, 106 (01) :9-12

[9] NMR CROSS-POLARIZATION BY ADIABATIC PASSAGE THROUGH THE HARTMANN-HAHN CONDITION (APHH) [J].

HEDIGER, S ;

MEIER, BH ;

KURUR, ND ;

BODENHAUSEN, G ;

ERNST, RR .

CHEMICAL PHYSICS LETTERS, 1994, 223 (04) :283-288

[10] A 140 GHz prepolarizer for dissolution dynamic nuclear polarization [J].

Jannin, S. ;

Comment, A. ;

Kurdzesau, F. ;

Konter, J. A. ;

Hautle, P. ;

van den Brandt, B. ;

van der Klink, J. J. .

JOURNAL OF CHEMICAL PHYSICS, 2008, 128 (24)

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