Outcomes of Polypharmacy in Nursing Home Residents

被引：65

作者：

Tamura, Bruce K. ^{[1
]}

Bell, Christina L. ^{[1
]}

Inaba, Michiko ^{[1
]}

Masaki, Kamal H. ^{[1
]}

机构：

[1] Univ Hawaii, John A Hartford Ctr Excellence Geriatr, Dept Geriatr Med, John A Burns Sch Med, Honolulu, HI 96817 USA

来源：

CLINICS IN GERIATRIC MEDICINE | 2012年 / 28卷 / 02期

关键词：

Long-term care; Polypharmacy; Nursing home; Outcomes; INAPPROPRIATE MEDICATION USE; LONG-TERM-CARE; ADVERSE DRUG-REACTIONS; RANDOMIZED CONTROLLED-TRIAL; ELDERLY-PEOPLE; OLDER-ADULTS; RISK-FACTORS; FACILITY CHARACTERISTICS; EXPLICIT CRITERIA; CONSENSUS PANEL;

D O I：

10.1016/j.cger.2012.01.005

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Our objective was to review the literature on outcomes of polypharmacy in the nursing home. Using MEDLINE, we reviewed primarily original, English language articles starting from 1990 that were specific to polypharmacy in nursing homes. We report on outcomes of potentially inappropriate medications, adverse drug events, drug-drug interactions, falls, fractures, hospitalizations, death and cost of polypharmacy. Our literature review found that polypharmacy was associated with increased use of potentially inappropriate drugs, adverse drug events, potential drug-drug interactions, hospitalizations, and higher cost. Polypharmacy was not consistently associated with falls, fractures, or mortality.

引用

页码：217 / +

页数：21

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