Protein demethylation required for DNA methylation

被引：5
|
作者：
Hotz, Hans-Rudolf [1 ]
Peters, Antoine H. F. M. [1 ]
机构：
[1] Friedrich Miescher Inst Biomed Res, CH-4058 Basel, Switzerland
来源：
NATURE GENETICS | 2009年 / 41卷 / 01期
关键词：
EMBRYONIC STEM-CELLS; PREIMPLANTATION DEVELOPMENT; CELLULAR-DIFFERENTIATION; GENE ACTIVATION; HISTONE H3; SPERMATOGENESIS; MAINTENANCE; LYSINE-4; MARK; LSD1;
D O I：
10.1038/ng0109-10
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
DNA methylation is an epigenetic mark directing stable, heritable gene silencing through development. a new study uncovers the importance of demethylation of the DNA methyltransferase-1 for maintenance of DNA methylation.
引用
收藏
页码：10 / 11
页数：3
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