Identification and analytical properties of new synthetic cannabimimetics bearing 2,2,3,3-tetramethylcyclopropanecarbonyl moiety

被引：35

作者：

Shevyrin, Vadim ^{[1
]}

Melkozerov, Vladimir ^{[2
]}

Nevero, Alexander ^{[3
]}

Eltsov, Oleg ^{[1
]}

Morzherin, Yuri ^{[1
]}

Shafran, Yuri ^{[1
]}

机构：

[1] Ural Fed Univ, Inst Chem & Technol, Ekaterinburg 620002, Russia

[2] Minist Interior Russian Federat, Sverdlovsk Reg Branch, Expert & Criminalist Ctr, Main Agcy, Ekaterinburg 620014, Russia

[3] Minist Internal Affairs Republ Belarus, State Expert & Criminalist Ctr, Minsk 220030, BELARUS

来源：

FORENSIC SCIENCE INTERNATIONAL | 2013年 / 226卷 / 1-3期

关键词：

(1H-indol-3-yl)( 2,2,3,3-tetramethylcyclopropyl)methanone; derivatives; A-836,339; Designer drugs; Cannabimimetics; GC-MS; NMR; LC-MS; CANNABINOIDS; KETONES; SPICE;

D O I：

10.1016/j.forsciint.2012.12.009

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

By means of gas chromatography with mass spectrometry detector (GC-MS), liquid chromatographymass spectrometry (LC-MS) and nuclear magnetic resonance spectroscopy (NMR), structure of a series from a novel class of synthetic cannabimimetics bearing 2,2,3,3-tetramethylcyclopropanecarbonyl moiety was established. It was found that this fragment could undergo thermal ring-opening into isomeric structures. The title compounds under action of hydrochloric acid can transform into new compounds which structure is discussed in the paper. The compounds identified could be referred to a new class of 'designer drugs' and are in illegal turnover in Russia and Belarus since the summer of 2011. Analytical data obtained in the paper will make possible reliable identification of such new 'designer drugs' during forensic examination. (C) 2012 Elsevier Ireland Ltd. All rights reserved.

引用

页码：62 / 73

页数：12

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