Atrial fibrillation and congestive heart failure

被引:37
|
作者
Roy, Denis [1 ]
Talajic, Mario
Dubuc, Marc
Thibault, Bernard
Guerra, Peter
Macle, Laurent
Khairy, Paul
机构
[1] Univ Montreal, Montreal Heart Inst, Montreal, PQ H1T 1C8, Canada
基金
加拿大健康研究院;
关键词
AF-CHF trial; atrial fibrillation; heart failure; LEFT-VENTRICULAR DYSFUNCTION; CARDIAC RESYNCHRONIZATION THERAPY; ACUTE MYOCARDIAL-INFARCTION; IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR; ANTIARRHYTHMIC DRUG-THERAPY; SINUS RHYTHM; PROGNOSTIC-SIGNIFICANCE; SYSTOLIC DYSFUNCTION; RANDOMIZED-TRIAL; MORTALITY;
D O I
10.1097/HCO.0b013e32831c8c58
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose of review The present review will examine the prognostic importance of atrial fibrillation and heart failure, explore the different therapeutic options for treating atrial fibrillation and present the results of the Atrial Fibrillation and Congestive Heart Failure (AF-CHF) trial. Recent findings The Atrial Fibrillation and Congestive Heart Failure trial was a randomized trial involving patients with both atrial fibrillation and heart failure. The trial was designed to compare the maintenance of sinus rhythm with the control of ventricular rate in patients with left ventricular dysfunction, heart failure and a history of atrial fibrillation. There was no significant difference in the rate of death from cardiovascular causes in the rhythm-control group as compared with the rate-control strategy. In addition, there was no significant difference in any of the secondary outcomes including death from any cause, worsening heart failure or stroke. The rate-control strategy eliminated the need for repeated cardioversion and reduced rates of hospitalization. Summary The results of the Atrial Fibrillation and Congestive Heart Failure trial indicate that a routine strategy of rhythm control does not reduce rate of death and suggest that rate control should be considered a primary approach for patients with atrial fibrillation and heart failure.
引用
收藏
页码:29 / 34
页数:6
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