Presence of Foveal Bulge in Optical Coherence Tomographic Images in Eyes With Macular Edema Associated With Branch Retinal Vein Occlusion

被引:44
作者
Hasegawa, Taiji [1 ]
Ueda, Tetsuo [1 ]
Okamoto, Masahiro [1 ]
Ogata, Nahoko [1 ]
机构
[1] Nara Med Univ, Dept Ophthalmol, Kashihara, Nara 6348522, Japan
关键词
INTRAVITREAL TRIAMCINOLONE; PHOTORECEPTOR LAYER; BEVACIZUMAB THERAPY; LASER TREATMENT; VISUAL-ACUITY; OCT PATTERNS; SECONDARY; DETACHMENT; INJECTION;
D O I
10.1016/j.ajo.2013.10.007
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
PURPOSE: To determine whether a significant correlation exists between the presence of a bulge in the photoreceptor inner segment/outer segment (IS-/OS) line and the best-corrected visual acuity (BCVA) in eyes with resolved macular edema associated with branch retinal vein occlusion (BRVO). DESIGN: Retrospective, observational case series. METHODS: We retrospectively reviewed the medical records of patients who had a complete resolution of macular edema and had an intact IS/OS line in the central fovea in the spectral-domain optical coherence tomographic (SDOCT) images. Thirty-one eyes with macular edema associated with BRVO (BRVO group) and 31 unaffected fellow eyes (control group) of 31 patients were evaluated. In normal eyes, the intact IS/OS line determined by SDOCT has a bulge at the central fovea, called the fovea! bulge. The eyes in the BRVO group were classified by the presence or absence of foveal bulge, and the characteristics of the 2 groups were compared. RESULTS: A foveal bulge was present in 7 of 31 eyes in the BRVO group. The incidence of a foveal bulge was significantly lower in the BRVO group (22.6%) than in the control group (100%; P <.0001). All 7 eyes with foveal bulge had a decimal BCVA of >= 1.0 at the final visit. The incidence of a foveal bulge was significantly higher in eyes with BCVA of >= 1.0 (77.8%) than in the eyes with BCVA of <1.0 (0%; P <.0001). CONCLUSIONS: The foveal bulge is a good marker of the functional properties of the fovea in eyes with resolved macular edema associated with BRVO. (C) 2014 by Elsevier Inc. All rights reserved.
引用
收藏
页码:390 / 396
页数:7
相关论文
共 25 条
[1]   Macular ultrastructural features in amblyopia using high-definition optical coherence tomography [J].
Al-Haddad, Christiane Elias ;
El Mollayess, Georges M. ;
Mahfoud, Ziyad R. ;
Jaafar, Dalida F. ;
Bashshur, Ziad F. .
BRITISH JOURNAL OF OPHTHALMOLOGY, 2013, 97 (03) :318-322
[2]  
Arnarsson A, 2000, INVEST OPHTH VIS SCI, V41, P877
[3]   Ranibizumab for Macular Edema following Branch Retinal Vein Occlusion Six-Month Primary End Point Results of a Phase III Study [J].
Campochiaro, Peter A. ;
Heier, Jeffrey S. ;
Feiner, Leonard ;
Gray, Sarah ;
Saroj, Namrata ;
Rundle, Amy Chen ;
Murahashi, Wendy Yee ;
Rubio, Roman G. .
OPHTHALMOLOGY, 2010, 117 (06) :1102-U111
[4]  
Çekiç O, 2005, RETINA-J RET VIT DIS, V25, P851
[5]  
Chen SDM, 2006, AM J OPHTHALMOL, V141, P876, DOI 10.1016/j.ajo.2005.12.011
[6]   Multiple laser treatments for macular edema attributable to branch retinal vein occlusion [J].
Esrick, E ;
Subramanian, ML ;
Heier, JS ;
Devaiah, AK ;
Topping, TM ;
Frederick, AR ;
Morley, MG .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 2005, 139 (04) :653-657
[7]   Histologic Development of the Human Fovea From Midgestation to Maturity [J].
Hendrickson, Anita ;
Possin, Daniel ;
Vajzovic, Lejla ;
Toth, Cynthia A. .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 2012, 154 (05) :767-778
[8]   OCT patterns of macular edema and response to bevacizumab therapy in retinal vein occlusion [J].
Hoeh, Alexandra Eva ;
Ruppenstein, Mira ;
Ach, Thomas ;
Dithmar, Stefan .
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2010, 248 (11) :1567-1572
[9]   Spectral-domain optical coherence tomography (SD-OCT) patterns and response to intravitreal bevacizumab therapy in macular edema associated with branch retinal vein occlusion [J].
Kang, Hae Min ;
Chung, Eun Jee ;
Kim, Yong Min ;
Koh, Hyoung Jun .
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2013, 251 (02) :501-508
[10]   INTRAVITREAL INJECTION OF BEVACIZUMAB FOR MACULAR EDEMA SECONDARY TO BRANCH RETINAL VEIN OCCLUSION Results After 12 Months and Multiple Regression Analysis [J].
Kondo, Mineo ;
Kondo, Nagako ;
Ito, Yasuki ;
Kachi, Shu ;
Kikuchi, Masato ;
Yasuma, Tetsuhiro R. ;
Ota, Ichiro ;
Miyake, Kensaku ;
Terasaki, Hiroko .
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 2009, 29 (09) :1242-1248