Synthesis, Molecular Modeling and Biological Evaluation of Indeno[1,2-b]iquinoxaline Derivatives as Antifungal and Antibacterial Agents

被引：4

作者：

Abd El Salam, Hayam A. ^{[1
]}

El-Bendary, Magda A. ^{[2
]}

Ibrahim, Medhat ^{[3
]}

El-Samahy, Fatma A. ^{[1
]}

机构：

[1] Natl Res Ctr, Chem Ind Res Div, Green Chem Dept, 33 El Bohouth St,PO 12622, Giza, Egypt

[2] Natl Res Ctr, Genet Engn & Biotechnol Div, Microbial Chem Dept, 33 El Bohouth St,PO 12622, Giza, Egypt

[3] Natl Res Ctr, Spect Dept, 33 El Bohouth St,PO 12622, Giza, Egypt

来源：

EGYPTIAN JOURNAL OF CHEMISTRY | 2020年 / 63卷 / 07期

关键词：

11H-Indeno [1,2-b]quinoxalin-2-one; Thiocarbohydrazides; 2-Chloroacetamide derivatives; Molecular modeling; Biologically activity; QUINOXALINE DERIVATIVES; KINASE; ANTICANCER; INHIBITORS; FULLERENE;

D O I：

10.21608/ejchem.2020.21366.2275

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

THE (11H-indemo[1,2-b]quinoxalin-11-ylidene)thiocarbohydrazone were synthesized and consequently some new novel structures were obtained in a good yields. Their chemical structures were assigned by means of spectral analysis. Molecular modeling at B3LYF/6-31 g (d, p) is utilized to calculate both the optimized structure and vibrational spectra of some studiexi structures. A promising antimicrobial result was obtained from the new synthesized compounds.

引用

页码：2577 / 2590

页数：14

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