Circumcision for the prevention of significant bacteriuria in boys

被引:35
作者
Nayir, A [1 ]
机构
[1] Istanbul Univ, Istanbul Fac Med, Pediat Nephrol Div, Dept Pediat, TR-80040 Gumussuyu Istanbul, Turkey
关键词
circumcision; urinary tract infection; ultrasonography; significant bacteriuria; male infant;
D O I
10.1007/s004670100044
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
The aim of this study was to determine whether circumcision affects significant bacteriuria in boys. During a 60-month prospective study, 100 boys with microbiologically confirmed symptomatic urinary tract infection (UTI) were evaluated. Twelve patients with abnormal ultrasonography findings were excluded from the study. Eighteen of the boys had not been circumcised due to parental choice. The remaining 70 boys with normal renal ultrasonography were randomly allocated into two groups. In the first group 35 boys ranging in age from 6 months to 10 years (mean 33.2+/-30.9 months) were observed for 6 months and urinary cultures were taken monthly. When they had a positive urine culture (with or without any symptoms), they received antibiotic treatment. After 6 months they were circumcised and then observed for another 6-month period. Group 2 comprised 35 boys aged from 3 months to 9 years (mean 29.1+/-36.7 months). They were circumcised immediately after the first UTI and were followed for 6 months. Urine samples were obtained by the bag technique in infants and by the mid-stream technique in older patients. In the uncircumcised group, the rate of significant bacteriuria per patient did not change in two 6-month follow-up periods (3.46+/-0.91 and 3.33+/-0.97 episodes). In group 1, the rate of positive urine cultures dropped from 3.57+/-1.11 to 0.14+/-0.35 episodes after circumcision (P<0.001). In the second group, the rate of significant bacteriuria was 0.17+/-0.38 episodes after circumcision. Among the uncircumcised patients, symptomatic UTI was observed in 6 cases Q cases in the first period of group 1, 1 case in the first and 2 cases in the second period of the uncircumcised group), whereas after circumcision no patient had symptomatic UTI. The mean age at circumcision was 42.7+/-28.4 months. No complication due to circumcision occurred in any patient. UTI may also occur in boys after the 1st year of life. The present study indicated that circumcision in boys decreases the rate of positive urine cultures. Therefore circumcision could be considered as a part of UTI therapy.
引用
收藏
页码:1129 / 1134
页数:6
相关论文
共 40 条
[1]  
ANDRICH MP, 1992, PEDIATRICS, V90, P436
[3]   BACTERIOLOGY OF MIDSTREAM CATCH URINES - STUDIES IN NEWBORN INFANTS [J].
BOEHM, JJ ;
HAYNES, JL .
AMERICAN JOURNAL OF DISEASES OF CHILDREN, 1966, 111 (04) :366-&
[4]  
Bonadio W A, 1987, Pediatr Emerg Care, V3, P75
[5]   Can circumcision prevent recurrent urinary tract infections in hospitalized infants? [J].
Cason, DL ;
Carter, BS ;
Bhatia, J .
CLINICAL PEDIATRICS, 2000, 39 (12) :699-703
[6]   CIRCUMCISION - IS THE RISK OF URINARY-TRACT INFECTION REALLY THE PIVOTAL ISSUE [J].
CHESSARE, JB .
CLINICAL PEDIATRICS, 1992, 31 (02) :100-104
[7]   Effect of circumcision on incidence of urinary tract infection in preschool boys [J].
Craig, JC ;
Knight, JF ;
Sureshkumar, P ;
Mantz, E ;
Roy, LP .
JOURNAL OF PEDIATRICS, 1996, 128 (01) :23-27
[8]   CIRCUMCISION COMPLICATION - REACTION TO TREATMENT OF LOCAL HEMORRHAGE WITH TOPICAL EPINEPHRINE IN HIGH-CONCENTRATION [J].
DENTON, J ;
SCHREINER, RL ;
PEARSON, J .
CLINICAL PEDIATRICS, 1978, 17 (03) :285-286
[9]  
Eke N, 2000, J NATL MED ASSOC, V92, P196
[10]   A study of clinical opinion and practice regarding circumcision [J].
Farshi, Z ;
Atkinson, KR ;
Squire, R .
ARCHIVES OF DISEASE IN CHILDHOOD, 2000, 83 (05) :393-396