CHEMOSELECTIVE C-BENZOYLATION OF PHENOLS BY USING ALCl3 UNDER SOLVENT-FREE CONDITIONS

被引：2

作者：

Gaikwad, Sunil V. ^{[1
]}

Nawghare, Beena R. ^{[1
]}

Lokhande, Pradeep D. ^{[1
]}

机构：

[1] Savitribaiphule Pune Univ, Dept Chem, Pune 411007, Maharashtra, India

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF ETHIOPIA | 2015年 / 29卷 / 02期

关键词：

Chemoselective C-acylation; F-C reaction; Fries rearrangement; FRIEDEL-CRAFTS ACYLATION; AROMATIC-COMPOUNDS; EFFICIENT SYNTHESIS; REARRANGEMENT; ACIDS; DEPROTECTION; ANALOGS; COMPLEX; KETONES; KINASE;

D O I：

10.4314/bcse.v29i2.14

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Substituted phenols were chemo-selectively reacted with benzoylchloride in presence of aluminum chloride under solvent-free condition to afford the corresponding 2'-hydroxy aryl benzophenones in excellent yields (72-96%). Naphthol benzoylation resulted in lower yields as compared to phenols. Both reactions completed in 5-10 min with quantitative yields providing excellent control over regioselectivity of products.

引用

页码：319 / 325

页数：7

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