Changes of the expressions of immune-related genes after ventromedial hypothalamic lesioning. Systematic review of the literature

被引:2
作者
Kiba, Takayoshi [1 ]
Yagyu, Kiyomi
机构
[1] Natl Hosp Org Kure Med Ctr, Div Modern Med Technol, Inst Clin Res, Kure 7370023, Japan
关键词
Immunity; Gene expression; Visceral organs; Hypothalamus; NEURON-RELATED GENES; NERVOUS-SYSTEM; LYMPHOID-TISSUE; CELL RESPONSES; BONE-MARROW; MICE; RECEPTOR; RAT; STIMULATION; 4-1BB;
D O I
10.1016/j.jneuroim.2013.01.010
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Over the past 20 years, the functional autonomy of both the immune and central nervous systems has been successfully challenged. Although the ventromedial hypothalamus (VMH) is one of the centers of parasympathetic nervous system, to date, there has been little reported regarding the role of the hypothalamus in directly changing the expression of immune-related genes. Recently, it has been reported that VMH lesions can directly change the expression of immune-related gene families. The present review focuses on the relationships between the VMH and the expressions of immune-related genes. (C) 2013 Elsevier B.V. All rights reserved.
引用
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页码:1 / 6
页数:6
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