Mn(III)-Mediated Cascade Cyclization of 3-Isocyano-[1,1′-biphenyl]-2-carbonitrile with Arylboronic Acid: Construction of Pyrrolopyridine Derivatives

被引：43
作者：
Xu, Pei
Zhu, Yi-Ming
Wang, Fei
Wang, Shun-Yi [1 ]
Ji, Shun-Jun [1 ]
机构：
[1] Soochow Univ, Key Lab Organ Synth Jiangsu Prov, Coll Chem Chem Engn & Mat Sci, Suzhou 215123, Peoples R China
来源：
ORGANIC LETTERS | 2019年 / 21卷 / 03期
基金：
中国国家自然科学基金;
关键词：
RADICAL CYCLIZATION; EFFICIENT SYNTHESIS; ISOCYANIDE INSERTION; CYANO MIGRATION; 2-ISOCYANOBIARYL; PHENANTHRIDINES; QUINOLINES; ALKENES; ACCESS;
D O I：
10.1021/acs.orglett.8b03868
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A Mn(III) mediated cascade cyclization of new designed multifunctionalized 3-isocyano-[1,1'-biphenyl]-2-carbonitrile with arylboronic acid to construct pyrrolopyridine derivatives is developed. A series of pyrroloporidine compounds have been constructed through the formation of two new C-C bonds and one C-N bond via a radical pathway.
引用
收藏
页码：683 / 686
页数：4
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