Virus entry: Open sesame

被引：901
作者：
Marsh, M
Helenius, A
机构：
[1] UCL, Cell Biol Unit, MRC, Mol Cell Biol Lab, London WC1E 6BT, England
[2] UCL, Cell Biol Unit, MRC, Dept Biochem & Mol Biol, London WC1E 6BT, England
[3] ETH Honggerberg, Inst Biochem, CH-8093 Zurich, Switzerland
来源：
CELL | 2006年 / 124卷 / 04期
基金：
英国医学研究理事会;
关键词：
D O I：
10.1016/j.cell.2006.02.007
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Detailed information about the replication cycle of viruses and their interactions with host organisms is required to develop strategies to stop them. Cell biology studies, live-cell imaging, and systems biology have started to illuminate the multiple and subtly different pathways that animal viruses use to enter host cells. These insights are revolutionizing our understanding of endocytosis and the movement of vesicles within cells. In addition, such insights reveal new targets for attacking viruses before they can usurp the host-cell machinery for replication.
引用
收藏
页码：729 / 740
页数：12
相关论文
共 102 条
  • [1] Membrane insertion of anthrax protective antigen and cytoplasmic delivery of lethal factor occur at different stages of the endocytic pathway
    Abrami, L
    Lindsay, M
    Parton, RG
    Leppla, SH
    van der Goot, FG
    [J]. JOURNAL OF CELL BIOLOGY, 2004, 166 (05) : 645 - 651
  • [2] ULTRASTRUCTURAL-STUDY OF ROTAVIRUS REPLICATION IN CULTURED-CELLS
    ALTENBURG, BC
    GRAHAM, DY
    ESTES, MK
    [J]. JOURNAL OF GENERAL VIROLOGY, 1980, 46 (JAN) : 75 - 85
  • [3] Bound simian virus 40 translocates to caveolin-enriched membrane domains, and its entry is inhibited by drugs that selectively disrupt caveolae
    Anderson, HA
    Chen, YZ
    Norkin, LC
    [J]. MOLECULAR BIOLOGY OF THE CELL, 1996, 7 (11) : 1825 - 1834
  • [4] Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease
    Berger, EA
    Murphy, PM
    Farber, JM
    [J]. ANNUAL REVIEW OF IMMUNOLOGY, 1999, 17 : 657 - 700
  • [5] Positional cloning of the mouse retrovirus restriction gene Fv1
    Best, S
    LeTissier, P
    Towers, G
    Stoye, JP
    [J]. NATURE, 1996, 382 (6594) : 826 - 829
  • [6] MECHANISM OF LYMPHOCYTIC CHORIOMENINGITIS VIRUS ENTRY INTO CELLS
    BORROW, P
    OLDSTONE, MBA
    [J]. VIROLOGY, 1994, 198 (01) : 1 - 9
  • [7] The structure of the poliovirus 135S cell entry intermediate at 10-Angstrom resolution reveals the location of an externalized polypeptide that binds to membranes
    Bubeck, D
    Filman, DJ
    Cheng, NQ
    Steven, AC
    Hogle, JM
    Belnap, DM
    [J]. JOURNAL OF VIROLOGY, 2005, 79 (12) : 7745 - 7755
  • [8] Large-plaque mutants of sindbis virus show reduced binding to heparan sulfate, heightened viremia, and slower clearance from the circulation
    Byrnes, AP
    Griffin, DE
    [J]. JOURNAL OF VIROLOGY, 2000, 74 (02) : 644 - 651
  • [9] DENDRITIC CELLS EXPOSED TO HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 TRANSMIT A VIGOROUS CYTOPATHIC INFECTION TO CD4+ T-CELLS
    CAMERON, PU
    FREUDENTHAL, PS
    BARKER, JM
    GEZELTER, S
    INABA, K
    STEINMAN, RM
    [J]. SCIENCE, 1992, 257 (5068) : 383 - 386
  • [10] Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection
    Chandran, K
    Sullivan, NJ
    Felbor, U
    Whelan, SP
    Cunningham, JM
    [J]. SCIENCE, 2005, 308 (5728) : 1643 - 1645
12345678910