Gold Nanorods: Controlling Their Surface Chemistry and Complete Detoxification by a Two-Step Place Exchange

被引：89

作者：

Kinnear, Calum ^{[1
]}

Dietsch, Herve ^{[1
]}

Clift, Martin J. D. ^{[1
]}

Endes, Carola ^{[1
]}

Rothen-Rutishauser, Barbara ^{[1
]}

Petri-Fink, Alke ^{[1
,2
]}

机构：

[1] Univ Fribourg, Adolphe Merkle Inst, CH-1723 Marly, Switzerland

[2] Univ Fribourg, Dept Chem, CH-1700 Fribourg, Switzerland

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2013年 / 52卷 / 07期

基金：

瑞士国家科学基金会;

关键词：

colloids; cytotoxicity; gold; nanorods; polymers; SIDE-BY-SIDE; CELLULAR UPTAKE; THIOL LIGANDS; NANOPARTICLES; SCATTERING; BROMIDE; SHAPE;

D O I：

10.1002/anie.201208568

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Surface functionalization: Complete detoxification of gold nanorods was achieved by manipulating the position in the stability map between surface-adsorbing polyethylene glycol (PEG) and destabilizing ethanol (see picture). This robust procedure complements studies related to the effects of shape when contemplating the nanoparticle-cell interaction. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：1934 / 1938

页数：5

共 38 条

[1] Conductometric studies of hexadecyltrimethylammonium bromide in aqueous solutions of ethanol and ethylene glycol [J].

Akbas, H ;

Kartal, Ç .

COLLOID JOURNAL, 2006, 68 (02) :125-130

[2] Cellular Uptake and Cytotoxicity of Gold Nanorods: Molecular Origin of Cytotoxicity and Surface Effects [J].

Alkilany, Alaaldin M. ;

Nagaria, Pratik K. ;

Hexel, Cole R. ;

Shaw, Timothy J. ;

Murphy, Catherine J. ;

Wyatt, Michael D. .

SMALL, 2009, 5 (06) :701-708

[3] Effects and uptake of gold nanoparticles deposited at the air-liquid interface of a human epithelial airway model [J].

Brandenberger, C. ;

Rothen-Rutishauser, B. ;

Muehlfeld, C. ;

Schmid, O. ;

Ferron, G. A. ;

Maier, K. L. ;

Gehr, P. ;

Lenz, A. -G. .

TOXICOLOGY AND APPLIED PHARMACOLOGY, 2010, 242 (01) :56-65

[4] Particles induce apical plasma membrane enlargement in epithelial lung cell line depending on particle surface area dose [J].

Brandenberger, Christina ;

Rothen-Rutishauser, Barbara ;

Blank, Fabian ;

Gehr, Peter ;

Muehlfeld, Christian .

RESPIRATORY RESEARCH, 2009, 10

[5] Nanotoxicology: a perspective and discussion of whether or not in vitro testing is a valid alternative [J].

Clift, Martin J. D. ;

Gehr, Peter ;

Rothen-Rutishauser, Barbara .

ARCHIVES OF TOXICOLOGY, 2011, 85 (07) :723-731

[6] Surface modification of gold nanorods through a place exchange reaction inside an ionic exchange resin [J].

Dai, Qiu ;

Coutts, Janelle ;

Zou, Jianhua ;

Huo, Qun .

CHEMICAL COMMUNICATIONS, 2008, (25) :2858-2860

[7] Characterizing Gold Nanorods in Solution Using Depolarized Dynamic Light Scattering [J].

Glidden, Michael ;

Muschol, Martin .

JOURNAL OF PHYSICAL CHEMISTRY C, 2012, 116 (14) :8128-8137

[8] Dynamics of place-exchange reactions on monolayer-protected gold cluster molecules [J].

Hostetler, MJ ;

Templeton, AC ;

Murray, RW .

LANGMUIR, 1999, 15 (11) :3782-3789

[9] A Reexamination of Active and Passive Tumor Targeting by Using Rod-Shaped Gold Nanocrystals and Covalently Conjugated Peptide Ligands [J].

Huang, Xiaohua ;

Peng, Xianghong ;

Wang, Yiqing ;

Wang, Yuxiang ;

Shin, Dong M. ;

El-Sayed, Mostafa A. ;

Nie, Shuming .

ACS NANO, 2010, 4 (10) :5887-5896

[10] Lateral diffusion of thiol ligands on the surface of Au nanoparticles: An electron paramagnetic resonance study [J].

Ionita, Petre ;

Volkov, Aleksei ;

Jeschke, Gunnar ;

Chechik, Victor .

ANALYTICAL CHEMISTRY, 2008, 80 (01) :95-106

← 1 2 3 4 →