Alzheimer's disease: Potential preventive, non-invasive, intervention strategies in lowering the risk of cognitive decline - A review study

被引:46
作者
Klimova, Blanka [1 ]
Kuca, Kamil [2 ,3 ]
机构
[1] Univ Hradec Kralove, Fac Informat & Management, Dept Appl Linguist, Hradec Kralove, Czech Republic
[2] Univ Hosp Hradec Kralove, Biomed Res Ctr, Hradec Kralove, Czech Republic
[3] Univ Hradec Kralove, Ctr Basic & Appl Res, Fac Informat & Management, Hradec Kralove, Czech Republic
关键词
Alzheimer's disease; Preclinical stage; Prevention; Non-invasive strategies; Cognitive decline; PHYSICAL-ACTIVITY; ASSOCIATION WORKGROUPS; DIAGNOSTIC GUIDELINES; NATIONAL INSTITUTE; DEMENTIA; IMPAIRMENT; BILINGUALISM; EXERCISE; AGE; RECOMMENDATIONS;
D O I
10.1016/j.jab.2015.07.004
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The number of elderly people nowadays is rapidly increasing, especially in the developed countries. This brings about serious problems such as occurrence of diseases connected with aging population. The most frequent aging disease seems to be Alzheimer's disease (AD). The purpose of this article is to briefly describe the individual phases of this disease with special focus on the preclinical stage of AD since in this phase people might be already affected by some brain changes but they are still mentally and physically healthy individuals. Thus, the main goal of this article is to explore the preventive, non-invasive, intervention strategies which can help people already in the preclinical period of AD to lower the risk of cognitive decline and in this way enable them to stay independent on the assistance of other people and constantly attempt to improve quality of their life even in the older age. Firstly, a method of literature review analyzing the data contained in the world's prestigious scientific database: Web of Science in the period of 1990-2014 is used. Secondly, a method of comparison of different research studies examining preventive, non-invasive, intervention strategies in lowering the risk of cognitive decline is applied. (C) 2015 Published by Elsevier Sp. z o.o. on behalf of Faculty of Health and Social Studies, University of South Bohemia in Ceske Budejovice.
引用
收藏
页码:257 / 261
页数:5
相关论文
共 43 条
[11]   Delaying the onset of Alzheimer disease Bilingualism as a form of cognitive reserve [J].
Craik, Fergus I. M. ;
Bialystok, Ellen ;
Freedman, Morris .
NEUROLOGY, 2010, 75 (19) :1726-1729
[12]   Cell cycle and Alzheimer's disease: studies in non-neuronal cells [J].
de las Cuevas, Natividad ;
Munoz, Ursula ;
Bartolome, Fernando ;
Esteras, Noemi ;
Alquezar, Carolina ;
Martin-Requero, Angeles .
JOURNAL OF APPLIED BIOMEDICINE, 2010, 8 (03) :121-130
[13]   Low molecular weight precursor applicable for Alzheimer disease drugs synthesis (AChE and BChE inhibition, BACE inhibition, antioxidant properties and in silico modulation) [J].
Drtinova, Lucie ;
Dobes, Petr ;
Pohanka, Miroslav .
JOURNAL OF APPLIED BIOMEDICINE, 2014, 12 (04) :285-290
[14]   Language impairment in Alzheimer's disease and benefits of acetylcholinesterase inhibitors [J].
Ferris, Steven H. ;
Farlow, Martin .
CLINICAL INTERVENTIONS IN AGING, 2013, 8 :1007-1014
[15]   Physical activity and risk of neurodegenerative disease: a systematic review of prospective evidence [J].
Hamer, M. ;
Chida, Y. .
PSYCHOLOGICAL MEDICINE, 2009, 39 (01) :3-11
[16]   Preventing Alzheimer disease with exercise? [J].
Karceski, Steven .
NEUROLOGY, 2012, 78 (17) :E110-E110
[17]   Alzheimer's disease - The ways of prevention [J].
Kivipelto, M. ;
Solomon, A. .
JOURNAL OF NUTRITION HEALTH & AGING, 2008, 12 (01) :89S-94S
[18]   Alzheimer's disease and language impairments: social intervention and medical treatment [J].
Klimova, Blanka ;
Maresova, Petra ;
Valis, Martin ;
Hort, Jakub ;
Kuca, Kamil .
CLINICAL INTERVENTIONS IN AGING, 2015, 10 :1401-1408
[19]   Is the risk of Alzheimer's disease and dementia declining? [J].
Langa, Kenneth M. .
ALZHEIMERS RESEARCH & THERAPY, 2015, 7
[20]   Alzheimer's disease, cerebrovascular dysfunction and the benefits of exercise: From vessels to neurons [J].
Lange-Asschenfeldt, Christian ;
Kojda, Georg .
EXPERIMENTAL GERONTOLOGY, 2008, 43 (06) :499-504